Background The innate immune system recalls a challenge to adapt to a secondary challenge,
a phenomenon called trained immunity. Training involves cellular metabolic, epigenetic …

Short chain fatty acids (SCFAs) produced by intestinal microbes mediate anti-inflammatory
effects, but whether they impact on antimicrobial host defenses remains largely unknown. …

Sirtuin 2 (SIRT2) is one of the seven members of the family of NAD + -dependent histone
deacetylases. Sirtuins target histones and non-histone proteins according to their subcellular …

Trained immunity refers to the ability of the innate immune system exposed to a first challenge
to provide an enhanced response to a secondary homologous or heterologous challenge. …

Sirtuin 3 (SIRT3) is the main mitochondrial deacetylase. SIRT3 regulates cell metabolism and
redox homeostasis, and protects from aging and age-associated pathologies. SIRT3 may …

The sirtuins SIRT3 and SIRT5 are the main mitochondrial lysine deacetylase and desuccinylase,
respectively. SIRT3 and SIRT5 regulate metabolism and redox homeostasis and have …

Objectives Biofilms are structured aggregates of bacteria embedded in a self-produced
matrix that develop in diverse ecological niches. Pathogenic bacteria can form biofilms on …

Sirtuin 2 (SIRT2) and SIRT3 are cytoplasmic and mitochondrial NAD-dependent deacetylases.
SIRT2 and SIRT3 target proteins involved in metabolic, proliferation and inflammation …

Sirtuin 5 (SIRT5) is a member of the family of NAD + -dependent lysine/histone deacetylases.
SIRT5 resides mainly in the mitochondria where it catalyzes deacetylation, demalonylation, …

Lactobacillus algidus is a meat spoilage bacterium often dominating the bacterial communities
on chilled, packaged meat. Yet, L. algidus strains are rarely recovered from meat, and …