User profiles for Tytus Bernaś

Tytus Bernas

Director of Microscopy Facility, Institute of Experimental Biology PAS
Verified email at nencki.gov.pl
Cited by 2446

Mitochondrial and nonmitochondrial reduction of MTT: Interaction of MTT with TMRE, JC‐1, and NAO mitochondrial fluorescent probes

T Bernas, J Dobrucki - … : The journal of the international society …, 2002 - Wiley Online Library
Background Bioreduction of water‐soluble tetrazolium salts (eg, MTS, XTT, and MTT) to
their respective formazans is generally regarded as an indicator of cell “redox activity.” The …

[HTML][HTML] MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2

…, I Bray, KM Watters, S Das, K Bryan, T Bernas… - Cell Death & …, 2011 - nature.com
MicroRNAs function as negative regulators of posttranscriptional gene expression, having
major roles in cellular differentiation. Several neuroblastoma cell lines can be induced to …

The role of plasma membrane in bioreduction of two tetrazolium salts, MTT, and CTC

T Bernas, JW Dobrucki - Archives of biochemistry and biophysics, 2000 - Elsevier
Despite widespread use of various tetrazolium assays, the mechanisms of bioreduction of
these compounds have not been fully elucidated. We investigated the capacity of tetrazolium …

[HTML][HTML] Neuronal plasticity affects correlation between the size of dendritic spine and its postsynaptic density

M Borczyk, MA Śliwińska, A Caly, T Bernas… - Scientific reports, 2019 - nature.com
Structural plasticity of dendritic spines is thought to underlie memory formation. Size of a
dendritic spine is considered proportional to the size of its postsynaptic density (PSD), number …

Luminescent fac-[Re (CO) 3 (phen)] carboxylato complexes with non-steroidal anti-inflammatory drugs: synthesis and mechanistic insights into the in vitro anticancer …

J Skiba, A Kowalczyk, P Stączek, T Bernaś… - New Journal of …, 2019 - pubs.rsc.org
Four fac-[Re(CO)3(phen)(L)] complexes with phen = 1,10-phenanthroline and L = a non-steroidal
anti-inflammatory drug (NSAID) carboxylate ligand were obtained from the reaction of …

[HTML][HTML] Low level phosphorylation of histone H2AX on serine 139 (γH2AX) is not associated with DNA double-strand breaks

P Rybak, A Hoang, L Bujnowicz, T Bernas, K Berniak… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Phosphorylation of histone H2AX on serine 139 (γH2AX) is an early step in cellular response
to a DNA double-strand break (DSB). γH2AX foci are generally regarded as markers of …

[HTML][HTML] Analysis of the Behavior of Mitochondria in the Ovaries of the Earthworm Dendrobaena veneta Rosa 1839

J Faron, T Bernaś, H Sas–Nowosielska, J Klag - PLoS One, 2015 - journals.plos.org
We examined six types of cells that form the ovary of the earthworm Dendrobena veneta
ogonia, prooocytes, vitellogenic oocytes, trophocytes, fully grown postvitellogenic oocytes and …

[HTML][HTML] Inhibition of SCD1 impairs palmitate-derived autophagy at the step of autophagosome-lysosome fusion in pancreatic β-cells

…, A Dziewulska, K Kozinski, P Dobrzyn, T Bernas… - Journal of lipid …, 2015 - ASBMB
Autophagy is indispensable for the proper architecture and flawless functioning of
pancreatic β-cells. A growing body of evidence indicates reciprocal communication between …

[HTML][HTML] Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice

…, K Barszcz, J Czarnecka, A Kowalczyk, T Bernas… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Anticancer therapies that induce DNA damage tend to trigger senescence in cancer cells, a
process known as therapy-induced senescence (TIS). Such cells may undergo atypical …

[HTML][HTML] Mitochondria targeting with luminescent rhenium (I) complexes

J Skiba, T Bernaś, D Trzybiński, K Woźniak, G Ferraro… - Molecules, 2017 - mdpi.com
Two new neutral fac-[Re(CO) 3 (phen)L] compounds (1,2), with phen = 1,10-phenanthroline
and L = O 2 C(CH 2 ) 5 CH 3 or O 2 C(CH 2 ) 4 C≡CH, were synthetized in one-pot …