Aged‐senescent cells contribute to impaired heart regeneration
…, PJ Ruchaya, E Domenjo‐Vila, T Shin Teoh… - Aging cell, 2019 - Wiley Online Library
Aging leads to increased cellular senescence and is associated with decreased potency of
tissue‐specific stem/progenitor cells. Here, we have done an extensive analysis of cardiac …
tissue‐specific stem/progenitor cells. Here, we have done an extensive analysis of cardiac …
Loss of FOCAD, operating via the SKI messenger RNA surveillance pathway, causes a pediatric syndrome with liver cirrhosis
R Moreno Traspas, TS Teoh, PM Wong, M Maier… - Nature …, 2022 - nature.com
Cirrhosis is usually a late-onset and life-threatening disease characterized by fibrotic scarring
and inflammation that disrupts liver architecture and function. While it is typically the result …
and inflammation that disrupts liver architecture and function. While it is typically the result …
[PDF][PDF] Loss of C2orf69 defines a fatal autoinflammatory syndrome in humans and zebrafish that evokes a glycogen-storage-associated mitochondriopathy
Human C2orf69 is an evolutionarily conserved gene whose function is unknown. Here, we
report eight unrelated families from which 20 children presented with a fatal syndrome …
report eight unrelated families from which 20 children presented with a fatal syndrome …
Loss of C2orf69 defines a fatal auto-inflammatory mitochondriopathy in Humans and Zebrafish
Human C2orf69 is an evolutionary-conserved gene whose function is unknown. Here, we
report 9 children from 5 unrelated families with a fatal syndrome consisting of severe auto-…
report 9 children from 5 unrelated families with a fatal syndrome consisting of severe auto-…
Senescent, dysfunctional human cardiac progenitor cells (CPCs) accumulate in the aged heart and elimination of senescent cells enhances CPC activation and …
…, PJ Ruchaya, E Domenjo-Vila, TS Teoh… - bioRxiv, 2018 - biorxiv.org
Rationale Aging leads to increased cellular senescence and is associated with decreased
potency of tissue-specific stem/progenitor cells. Objective To determine the impact of ageing …
potency of tissue-specific stem/progenitor cells. Objective To determine the impact of ageing …
Canonical Wnt signaling reverses the 'aged/senescent'phenotype of human endogenous cardiac stem cells
FC Lewis, TS Teoh, E Domenj?-Vila, T Theologou… - Circulation, 2016 - Am Heart Assoc
The adult human myocardium harbours endogenous, multi-potent cardiac stem cells (eCSCs),
however aging/senescence of eCSCs determines their function and regenerative capacity…
however aging/senescence of eCSCs determines their function and regenerative capacity…
[PDF][PDF] Loss of C2orf69 defines a fatal autoinflammatory syndrome in humans and zebrafish that evokes a glycogen storage-associated mitochondriopathy
NA Akarsu, S Maurer-Stroh, A Cetinkaya… - STAR - core.ac.uk
Human C2orf69 is an evolutionarily conserved gene whose function is unknown. Here, we
report eight unrelated families from which 20 children presented with a fatal syndrome …
report eight unrelated families from which 20 children presented with a fatal syndrome …
[PDF][PDF] Nurten A. Akarsu, 3 Sebastian Maurer-Stroh, 14 Arda Cetinkaya, 3 Aida Bertoli-Avella, 36
Human C2orf69 is an evolutionarily conserved gene whose function is unknown. Here, we
report eight unrelated families from which 20 children presented with a fatal syndrome …
report eight unrelated families from which 20 children presented with a fatal syndrome …
Loss of Focad, Operating in the SKI mRNA Surveillance Pathway, is Responsible for a Syndromic form of Pediatric Liver Cirrhosis
RM Traspas - 2022 - search.proquest.com
The human liver is endowed with intrinsic capability to regenerate upon injury. However,
when damage and inflammation persist, the organ may lose its regenerative potential leading …
when damage and inflammation persist, the organ may lose its regenerative potential leading …
Building a thematic framework of cybersecurity: a systematic literature review approach
Purpose This paper aims to explore the factors affecting cybersecurity implementation in
organizations in various countries and develop a cybersecurity framework to improve …
organizations in various countries and develop a cybersecurity framework to improve …