[HTML][HTML] Emerging applications of nanoparticles for lung cancer diagnosis and therapy
Lung cancer is by far the leading cause of cancer-related mortality worldwide, most of them
being active tobacco smokers. Non small cell lung cancer accounts for around 85% to 90% …
being active tobacco smokers. Non small cell lung cancer accounts for around 85% to 90% …
Remote Control of Time‐Regulated Stretching of Ligand‐Presenting Nanocoils In Situ Regulates the Cyclic Adhesion and Differentiation of Stem Cells
…, YS Jeon, HS Park, YJ Kim, UK Sukumar… - Advanced …, 2021 - Wiley Online Library
Native extracellular matrix (ECM) can exhibit cyclic nanoscale stretching and shrinking of
ligands to regulate complex cell–material interactions. Designing materials that allow cyclic …
ligands to regulate complex cell–material interactions. Designing materials that allow cyclic …
Intranasal delivery of targeted polyfunctional gold–iron oxide nanoparticles loaded with therapeutic microRNAs for combined theranostic multimodality imaging and …
UK Sukumar, RJC Bose, M Malhotra, HA Babikir… - Biomaterials, 2019 - Elsevier
The prognosis for glioblastoma (GBM) remains depressingly low. The biological barriers of
the brain present a major challenge to achieving adequate drug concentrations for GBM …
the brain present a major challenge to achieving adequate drug concentrations for GBM …
Reconstructed apoptotic bodies as targeted “nano decoys” to treat intracellular bacterial infections within macrophages and cancer cells
…, N Tharmalingam, FJ Garcia Marques, UK Sukumar… - ACS …, 2020 - ACS Publications
Staphylococcus aureus (S. aureus) is a highly pathogenic facultative anaerobe that in some
instances resides as an intracellular bacterium within macrophages and cancer cells. This …
instances resides as an intracellular bacterium within macrophages and cancer cells. This …
Camouflaged Hybrid Cancer Cell‐Platelet Fusion Membrane Nanovesicles Deliver Therapeutic MicroRNAs to Presensitize Triple‐Negative Breast Cancer to …
Camouflaged cell‐membrane‐based nanoparticles have gained increasing attention owing
to their improved biocompatibility and immunomodulatory properties. Using nanoparticles …
to their improved biocompatibility and immunomodulatory properties. Using nanoparticles …
Ultrasound/microbubble-mediated targeted delivery of anticancer microRNA-loaded nanoparticles to deep tissues in pigs
In this study, we designed and validated a platform for ultrasound and microbubble-mediated
delivery of FDA-approved pegylated poly lactic-co-glycolic acid (PLGA) nanoparticles …
delivery of FDA-approved pegylated poly lactic-co-glycolic acid (PLGA) nanoparticles …
Local sound speed estimation for pulse-echo ultrasound in layered media
…, AV Telichko, H Wang, UK Sukumar… - IEEE transactions on …, 2021 - ieeexplore.ieee.org
Our previous methodology in local sound speed estimation utilized time delays measured by
the cross correlation of delayed full-synthetic aperture channel data to estimate the average …
the cross correlation of delayed full-synthetic aperture channel data to estimate the average …
[HTML][HTML] Ultrasound-mediated delivery of miRNA-122 and anti-miRNA-21 therapeutically immunomodulates murine hepatocellular carcinoma in vivo
…, R Devulapally, R Afjei, UK Sukumar… - Journal of controlled …, 2020 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common cause of cancer-related mortality, and
patients with HCC show poor response to currently available treatments, which demands …
patients with HCC show poor response to currently available treatments, which demands …
Immunoregulation of macrophages by controlling winding and unwinding of nanohelical ligands
…, JH Moon, YJ Kim, UK Sukumar… - Advanced Functional …, 2021 - Wiley Online Library
Developing materials with the capability of changing their innate features can help to unravel
direct interactions between cells and ligand‐displaying features. This study demonstrates …
direct interactions between cells and ligand‐displaying features. This study demonstrates …
SP94-Targeted Triblock Copolymer Nanoparticle Delivers Thymidine Kinase–p53–Nitroreductase Triple Therapeutic Gene and Restores Anticancer Function against …
UK Sukumar, JCB Rajendran, SS Gambhir… - … applied materials & …, 2020 - ACS Publications
Gene-directed enzyme–prodrug therapy (GDEPT) is a promising approach for cancer
therapy, but it suffers from poor targeted delivery in vivo. Polyethylenimine (PEI) is a cationic …
therapy, but it suffers from poor targeted delivery in vivo. Polyethylenimine (PEI) is a cationic …