We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …

Here we report the Simons Genome Diversity Project data set: high quality genomes from 300
individuals from 142 diverse populations. These genomes include at least 5.8 million base …

Background The cause of most fetal anomalies is not determined prenatally. Exome sequencing
has transformed genetic diagnosis after birth, but its usefulness for prenatal diagnosis is …

The diagnostic yield of exome sequencing (ES) has primarily been evaluated in individuals
of European ancestry, with less focus on underrepresented minority (URM) and underserved …

Turkey has experienced major population movements. Population structure and genetic
relatedness of samples from three regions of Turkey, using over 500,000 SNP genotypes, were …

Krüppel-like transcription factors (KLFs) have elicited significant attention because of their
regulation of essential biochemical pathways and, more recently, because of their …

The metabolic syndrome (MetS) is a common disorder, where systemic insulin-resistance is
associated with increased risk for type 2 diabetes (T2D) and cardiovascular disease. …

ANKRD17 is an ankyrin repeat-containing protein thought to play a role in cell cycle progression,
whose ortholog in Drosophila functions in the Hippo pathway as a co-factor of Yorkie. …

Low levels of high density lipoprotein cholesterol (HDL-C) are an independent risk factor for
coronary heart disease. The Turkish Heart Study revealed very low levels of plasma HDL-C …

Background Next-generation sequencing is increasingly used in prenatal diagnosis. Targeted
gene panels and exome sequencing are both available, but the comparative diagnostic …