User profiles for U. Irion
Uwe IrionMax Planck Institut für Entwicklungsbiologie Verified email at tuebingen.mpg.de Cited by 1877 |
The developmental genetics of vertebrate color pattern formation: lessons from zebrafish
Color patterns are prominent features of many animals; they are highly variable and evolve
rapidly leading to large diversities even within a single genus. As targets for natural as well …
rapidly leading to large diversities even within a single genus. As targets for natural as well …
[HTML][HTML] The identification of genes involved in the evolution of color patterns in fish
U Irion, C Nüsslein-Volhard - Current Opinion in Genetics & Development, 2019 - Elsevier
The genetic basis of morphological variation, both within and between species, provides a
major topic in evolutionary biology. Teleost fish produce most elaborate color patterns, and …
major topic in evolutionary biology. Teleost fish produce most elaborate color patterns, and …
Precise and efficient genome editing in zebrafish using the CRISPR/Cas9 system
U Irion, J Krauss, C Nüsslein-Volhard - Development, 2014 - journals.biologists.com
The introduction of engineered site-specific DNA endonucleases has brought precise
genome editing in many model organisms and human cells into the realm of possibility. In …
genome editing in many model organisms and human cells into the realm of possibility. In …
bicoid RNA localization requires specific binding of an endosomal sorting complex
U Irion, D St Johnston - Nature, 2007 - nature.com
… Uwe Irion and Daniel St Johnston have now identified the specificity factor that couples
the RNA to the localization pathway as the ESCRT-II complex. ESCRT-II is involved in sorting …
the RNA to the localization pathway as the ESCRT-II complex. ESCRT-II is involved in sorting …
Developmental genetics with model organisms
U Irion, C Nüsslein-Volhard - Proceedings of the National …, 2022 - National Acad Sciences
In Darwin’s and Mendel’s times, researchers investigated a wealth of organisms, chosen to
solve particular problems for which they seemed especially well suited. Later, a focus on a …
solve particular problems for which they seemed especially well suited. Later, a focus on a …
[PDF][PDF] Pigment cell progenitors in zebrafish remain multipotent through metamorphosis
…, P Mahalwar, U Schach, C Linker, U Irion… - Developmental cell, 2016 - cell.com
The neural crest is a transient, multipotent embryonic cell population in vertebrates giving
rise to diverse cell types in adults via intermediate progenitors. The in vivo cell-fate potential …
rise to diverse cell types in adults via intermediate progenitors. The in vivo cell-fate potential …
Gap junctions composed of connexins 41.8 and 39.4 are essential for colour pattern formation in zebrafish
U Irion, HG Frohnhöfer, J Krauss, T Çolak Champollion… - Elife, 2014 - elifesciences.org
10.7554/eLife.05125.001 Interactions between all three pigment cell types are required to
form the stripe pattern of adult zebrafish (Danio rerio), but their molecular nature is poorly …
form the stripe pattern of adult zebrafish (Danio rerio), but their molecular nature is poorly …
ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells
A Fadeev, P Mendoza-Garcia, U Irion… - Proceedings of the …, 2018 - National Acad Sciences
Mutations in anaplastic lymphoma kinase (ALK) are implicated in somatic and familial
neuroblastoma, a pediatric tumor of neural crest-derived tissues. Recently, biochemical analyses …
neuroblastoma, a pediatric tumor of neural crest-derived tissues. Recently, biochemical analyses …
Control of cell fates and segmentation in the Drosophila mesoderm
V Riechmann, U Irion, R Wilson… - …, 1997 - journals.biologists.com
The primordia for heart, fat body, and visceral and somatic muscles arise in specific areas of
each segment in the Drosophila mesoderm. We show that the primordium of the somatic …
each segment in the Drosophila mesoderm. We show that the primordium of the somatic …
Endothelin signalling in iridophore development and stripe pattern formation of zebrafish
…, B Walderich, HM Maischein, C Weiler, U Irion… - Biology …, 2014 - journals.biologists.com
Colour patterns of adult fish are composed of several different types of pigment cells distributing
in the skin during juvenile development. The zebrafish, Danio rerio, displays a striking …
in the skin during juvenile development. The zebrafish, Danio rerio, displays a striking …