Cortical gamma oscillations (20-80 Hz) predict increases in focused attention, and failure in
gamma regulation is a hallmark of neurological and psychiatric disease. Current theory …

Spontaneous and sensory-evoked cortical activity is highly state-dependent, yet relatively little
is known about transitions between distinct waking states. Patterns of activity in mouse V1 …

A major long-term goal of systems neuroscience is to identify the different roles of neural
subtypes in brain circuit function. The ability to causally manipulate selective cell types is critical …

Modern genetic approaches are powerful in providing access to diverse cell types in the brain
and facilitating the study of their function. Here, we report a large set of driver and reporter …

We describe a quantitative theory to account for the computations performed by the feedforward
path of the ventral stream of visual cortex and the local circuits implementing them. We …

Human and non-human primates excel at visual recognition tasks. The primate visual system
exhibits a strong degree of selectivity while at the same time being robust to changes in the …

Behaviors and brain disorders involve neural circuits that are widely distributed in the brain.
The ability to map the functional connectivity of distributed circuits, and to assess how this …

To understand how the brain processes sensory information to guide behavior, we must know
how stimulus representations are transformed throughout the visual cortex. Here we report …

Fluorescent calcium indicators are often used to investigate neural dynamics, but the relationship
between fluorescence and action potentials (APs) remains unclear. Most APs can be …

The blood oxygenation level-dependent (BOLD) signal serves as the basis for human
functional MRI (fMRI). Knowledge of the properties of the BOLD signal, such as how linear its …