User profiles for Ulrich F Keyser
Ulrich F. KeyserProfessor of Applied Physics, Cavendish Lab, University of Cambridge Verified email at cam.ac.uk Cited by 15693 |
Salt dependence of ion transport and DNA translocation through solid-state nanopores
We report experimental measurements of the salt dependence of ion transport and DNA
translocation through solid-state nanopores. The ionic conductance shows a three-order-of-…
translocation through solid-state nanopores. The ionic conductance shows a three-order-of-…
Digitally encoded DNA nanostructures for multiplexed, single-molecule protein sensing with nanopores
The simultaneous detection of a large number of different analytes is important in bionanotechnology
research and in diagnostic applications. Nanopore sensing is an attractive method …
research and in diagnostic applications. Nanopore sensing is an attractive method …
Controlling molecular transport through nanopores
UF Keyser - Journal of The Royal Society Interface, 2011 - royalsocietypublishing.org
Nanopores are emerging as powerful tools for the detection and identification of macromolecules
in aqueous solution. In this review, we discuss the recent development of active and …
in aqueous solution. In this review, we discuss the recent development of active and …
Detecting DNA folding with nanocapillaries
We demonstrate for the first time the detection of the folding state of double-stranded DNA in
nanocapillaries with the resistive pulse technique. We show that glass capillaries can be …
nanocapillaries with the resistive pulse technique. We show that glass capillaries can be …
Real-time deformability cytometry: on-the-fly cell mechanical phenotyping
We introduce real-time deformability cytometry (RT-DC) for continuous cell mechanical
characterization of large populations (>100,000 cells) with analysis rates greater than 100 cells/s. …
characterization of large populations (>100,000 cells) with analysis rates greater than 100 cells/s. …
[HTML][HTML] DNA origami based assembly of gold nanoparticle dimers for surface-enhanced Raman scattering
Plasmonic sensors are extremely promising candidates for label-free single-molecule analysis
but require exquisite control over the physical arrangement of metallic nanostructures. …
but require exquisite control over the physical arrangement of metallic nanostructures. …
[HTML][HTML] Direct force measurements on DNA in a solid-state nanopore
Among the variety of roles for nanopores in biology, an important one is enabling polymer
transport, for example in gene transfer between bacteria 1 and transport of RNA through the …
transport, for example in gene transfer between bacteria 1 and transport of RNA through the …
[HTML][HTML] Origin of the electrophoretic force on DNA in solid-state nanopores
Despite gel electrophoresis being one of the main workhorses of molecular biology, the
physics of polyelectrolyte electrophoresis in a strongly confined environment remains poorly …
physics of polyelectrolyte electrophoresis in a strongly confined environment remains poorly …
Noise in solid-state nanopores
RMM Smeets, UF Keyser… - Proceedings of the …, 2008 - National Acad Sciences
We study ionic current fluctuations in solid-state nanopores over a wide frequency range and
present a complete description of the noise characteristics. At low frequencies (f ≲ 100 Hz) …
present a complete description of the noise characteristics. At low frequencies (f ≲ 100 Hz) …
DNA origami nanopores
We demonstrate the assembly of functional hybrid nanopores for single molecule sensing
by inserting DNA origami structures into solid-state nanopores. In our experiments, single …
by inserting DNA origami structures into solid-state nanopores. In our experiments, single …