[PDF][PDF] Comprehensive transcriptional analysis of early-stage urothelial carcinoma

…, MBH Thomsen, MM Nielsen, M Marquez, U Segersten… - Cancer cell, 2016 - cell.com
Non-muscle-invasive bladder cancer (NMIBC) is a heterogeneous disease with widely
different outcomes. We performed a comprehensive transcriptional analysis of 460 early-stage …

[HTML][HTML] An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer

…, CD Hurst, JD Raman, JI Warrick, U Segersten… - Nature …, 2021 - nature.com
The molecular landscape in non-muscle-invasive bladder cancer (NMIBC) is characterized
by large biological heterogeneity with variable clinical outcomes. Here, we perform an …

25-Hydroxyvitamin D3-1α-Hydroxylase Expression in Normal and Pathological Parathyroid Glands

U Segersten, P Correa, M Hewison… - The Journal of …, 2002 - academic.oup.com
Active vitamin D, 1,25-dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ], plays a pivotal role in calcium
homeostasis and bone metabolism. Circulating levels of 1,25(OH) 2 D 3 are thought to be …

Validation of a DNA methylation-mutation urine assay to select patients with hematuria for cystoscopy

…, M Márquez, TF Ørntoft, FX Real, U Segersten… - The Journal of …, 2017 - auajournals.org
Purpose : Only 3% to 28% of patients referred to the urology clinic for hematuria are diagnosed
with bladder cancer. Cystoscopy leads to high diagnostic costs and a high patient burden…

Proteomic analysis of urinary biomarker candidates for nonmuscle invasive bladder cancer

M Lindén, SB Lind, C Mayrhofer, U Segersten… - …, 2012 - Wiley Online Library
Nonmuscle invasive tumors of the bladder often recur and thereby bladder cancer patients
need regular re‐examinations which are invasive, unpleasant, and expensive. A noninvasive …

Prognostic impact of a 12-gene progression score in non–muscle-invasive bladder cancer: a prospective multicentre validation study

…, K Mogensen, W Beukers, M Marquez, U Segersten… - European Urology, 2017 - Elsevier
Background Progression of non–muscle-invasive bladder cancer (NMIBC) to muscle-invasive
bladder cancer (MIBC) is life-threatening and cannot be accurately predicted using clinical …

Molecular markers increase precision of the european association of urology non–muscle-invasive bladder cancer progression risk groups

…, F Algaba, NYC Welvaart, W Beukers, U Segersten… - Clinical Cancer …, 2018 - AACR
Purpose: The European Association of Urology (EAU) guidelines for non–muscle-invasive
bladder cancer (NMIBC) recommend risk stratification based on clinicopathologic parameters. …

[HTML][HTML] Risk prediction scores for recurrence and progression of non-muscle invasive bladder cancer: an international validation in primary tumours

…, ML Calle, L Dyrskjøt, M Kogevinas, U Segersten… - PloS one, 2014 - journals.plos.org
Objective We aimed to determine the validity of two risk scores for patients with non-muscle
invasive bladder cancer in different European settings, in patients with primary tumours. …

[HTML][HTML] Cathepsin E, maspin, Plk1, and survivin are promising prognostic protein markers for progression in non-muscle invasive bladder cancer

…, F Mansilla, M Sanchez-Carbayo, U Segersten… - The American journal of …, 2012 - Elsevier
Bladder cancer is a common cancer with particularly high recurrence after transurethral
resection. In this study, we investigated the prognostic value of the protein expression of …

Impact of thawing on RNA integrity and gene expression analysis in fresh frozen tissue

J Botling, K Edlund, U Segersten… - Diagnostic Molecular …, 2009 - journals.lww.com
Biobanks of fresh, unfixed human tissue represent a valuable source for gene expression
analysis in translational research and molecular pathology. The aim of this study was to …