(WTCCC2) consortia is provided in the Supplementary Note online. Author Contributions FC,
ADB, CEMG, J. Kere., A. Reis, JNB and RCT oversaw cohort collection for both the …

The underlying cause of mental retardation remains unknown in up to 80% of patients. As
chromosomal aberrations are the most common known cause of mental retardation, several …

Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …

Psoriatic arthritis (PsA) is an inflammatory joint disease that is distinct from other chronic
arthritides and which is frequently accompanied by psoriasis vulgaris (PsV) and seronegativity …

Variants in two genes of the IL-23 receptor (R) pathway have recently been shown to be
associated with psoriasis vulgaris (PV). We were interested whether the risk conferred by these …

1 Willemze R, Jaffe ES, Burg G et al. WHO-EORTC classification for cutaneous lymphomas.
Blood 2005; 105: 3768–85. 2 Phan NQ, Blome C, Fritz F et al. Assessment of pruritus …

Objective Single‐nucleotide polymorphisms (SNPs) of the tumor necrosis factor gene TNF
at positions −238 and −308 have been associated with psoriasis vulgaris and psoriatic …

Introduction: Clinical variability associated with the common 22q11.2 microdeletion is well
known, and has led to a broad application of FISH diagnostics with probes for loci TUPLE1 or …

Generalized pustular psoriasis (GPP) is a rare disorder affecting about 2 per million individuals
in Europe (Augey et al., 2006). This severe disease is characterized by repeated flare-…

Psoriasis is a common inflammatory skin disease with a strong genetic component. We
analyzed the genomic copy number polymorphism of the β-defensin region on human …