Antibiotic resistance is one of the major challenges facing modern medicine worldwide. The
past few decades have witnessed rapid progress in our understanding of the multiple factors …

Although they are abundant and even dominant members of animal microbiomes (microbiotas),
from sponges and termites to mice and cattle, archaea in our own microbiomes have …

Revealing the ecological principles that shape communities is a major challenge of the post-genomic
era. To date, a systematic approach for describing inter-species interactions has …

Oscillospira is an enigmatic bacterial genus that has never been cultured, but is constantly
detected by 16S rRNA gene surveys of the human microbiome. Here we summarize recent …

Culturing microorganisms is a critical step in understanding and utilizing microbial life. Here
we map the landscape of existing culture media by extracting natural-language media …

In their natural environments, microorganisms form complex systems of interactions. Understating
the structure and organization of bacterial communities is likely to have broad medical …

A leading hypothesis for the role of bacteria in inflammatory bowel diseases is that an
imbalance in normal gut flora is a prerequisite for inflammation. Testing this hypothesis requires …

Type III secretion systems (TTSS) are unique bacterial mechanisms that mediate elaborate
interactions with their hosts. The fact that several of the TTSS proteins are closely related to …

Bdellovibrio and like organisms (BALO) are obligate predators of Gram-negative bacteria,
belonging to the α- and δ-proteobacteria. BALO prey using either a periplasmic or an epibiotic …

Deciphering the modular organization of metabolic networks and understanding how
modularity evolves have attracted tremendous interest in recent years. Here, we present a …