Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery

…, S Brewerton, V Chelliah… - … of the Royal …, 2006 - royalsocietypublishing.org
Impressive progress in genome sequencing, protein expression and high-throughput
crystallography and NMR has radically transformed the opportunities to use protein three-…

[HTML][HTML] Wnt pathway in bone repair and regeneration–what do we know so far

…, D Popp, D Duscher, ZN Maan, MP Chelliah… - Frontiers in cell and …, 2019 - frontiersin.org
Wnt signaling plays a central regulatory role across a remarkably diverse range of functions
during embryonic development, including those involved in the formation of bone and …

Hypoglycaemia in elderly patients with diabetes mellitus: causes and strategies for prevention

A Chelliah, MR Burge - Drugs & aging, 2004 - Springer
Achieving target glycaemic goals while avoiding hypoglycaemia is a major challenge in the
management of elderly patients with diabetes mellitus. Repeated episodes of …

[HTML][HTML] The NCEP climate forecast system reanalysis

…, A Kumar, W Wang, C Long, M Chelliah… - Bulletin of the …, 2010 - journals.ametsoc.org
The NCEP Climate Forecast System Reanalysis (CFSR) was completed for the 31-yr period
from 1979 to 2009, in January 2010. The CFSR was designed and executed as a global, …

The NCEP/NCAR 40-year reanalysis project

…, G White, J Woollen, Y Zhu, M Chelliah… - Renewable …, 2018 - taylorfrancis.com
This chapter aims to update the documentation of the National Centers for Environmental
Prediction (NCEP)/ National Center for Atmospheric Research (NCAR) system design, output, …

The NCEP–NCAR 50-year reanalysis: monthly means CD-ROM and documentation

…, S Saha, G White, J Woollen, M Chelliah… - Bulletin of the American …, 2001 - JSTOR
The National Centers for Environmental Prediction (NCEP) and National Center for Atmospheric
Research (NCAR) have cooperated in a project (denoted “reanalysis”) to produce a …

[HTML][HTML] Compassionate use of remdesivir for patients with severe Covid-19

…, S Ahmed, J Bernett, D Chelliah… - … England Journal of …, 2020 - Mass Medical Soc
Background Remdesivir, a nucleotide analogue prodrug that inhibits viral RNA polymerases,
has shown in vitro activity against SARS-CoV-2. Methods We provided remdesivir on a …

[HTML][HTML] A comparison of immediate angioplasty with thrombolytic therapy for acute myocardial infarction

…, P Overlie, B Donohue, N Chelliah… - … England Journal of …, 1993 - Mass Medical Soc
Background The success of thrombolytic therapy for acute myocardial infarction is limited by
bleeding complications, the impossibility of reperfusing all occluded coronary arteries, …

[HTML][HTML] Climate assessment for 1999

…, R Tinker, W Thiaw, M Chelliah… - Bulletin of the …, 2000 - journals.ametsoc.org
The global climate during 1999 was impacted by Pacific cold episode (La Niña) conditions
throughout the year, which resulted in regional precipitation and atmospheric circulation …

Increases in platelet and red cell counts, blood viscosity, and arterial pressure during mild surface cooling: factors in mortality from coronary and cerebral thrombosis in …

…, F Cotter, M Mattock, M Murphy, R Chelliah - Br Med J (Clin Res …, 1984 - bmj.com
Six hours of mild surface cooling in moving air at 24 degrees C with little fall in core
temperature (0.4 degree C) increased the packed cell volume by 7% and increased the platelet …