Magnetic resonance tracking of transplanted bone marrow and embryonic stem cells labeled by iron oxide nanoparticles in rat brain and spinal cord
…, J Kroupová, B Andersson, V Bryja… - Journal of …, 2004 - Wiley Online Library
Nuclear magnetic resonance (MR) imaging provides a noninvasive method for studying the
fate of transplanted cells in vivo. We studied, in animals with a cortical photochemical lesion …
fate of transplanted cells in vivo. We studied, in animals with a cortical photochemical lesion …
The Frizzled family of unconventional G-protein-coupled receptors
G Schulte, V Bryja - Trends in pharmacological sciences, 2007 - cell.com
The Frizzled (FZD) family of receptors is critically involved in embryogenesis, and there is
substantial evidence that members of this family also regulate tissue homeostasis in many …
substantial evidence that members of this family also regulate tissue homeostasis in many …
Derivation of mouse embryonic stem cells
V Bryja, S Bonilla, E Arenas - Nature protocols, 2006 - nature.com
Here we describe a simple and efficient protocol for derivation of germline chimera-competent
mouse embryonic stem cells (mESCs) from embryonic day 3.5 (E3.5) blastocysts. The …
mouse embryonic stem cells (mESCs) from embryonic day 3.5 (E3.5) blastocysts. The …
β-Arrestin is a necessary component of Wnt/β-catenin signaling in vitro and in vivo
V Bryja, D Gradl, A Schambony… - Proceedings of the …, 2007 - National Acad Sciences
The Wnt/β-catenin signaling pathway is crucial for proper embryonic development and tissue
homeostasis. The phosphoprotein dishevelled (Dvl) is an integral part of Wnt signaling and …
homeostasis. The phosphoprotein dishevelled (Dvl) is an integral part of Wnt signaling and …
Mitogen-activated protein kinases promote WNT/β-catenin signaling via phosphorylation of LRP6
…, A Kozubík, G Schulte, JS Gutkind, V Bryja - … and cellular biology, 2011 - Taylor & Francis
LDL-related protein 6 (LRP6) is a coreceptor of WNTs and a key regulator of the WNT/β-catenin
pathway. Upon activation, LRP6 is phosphorylated within its intracellular PPPS/TP motifs…
pathway. Upon activation, LRP6 is phosphorylated within its intracellular PPPS/TP motifs…
The planar cell polarity pathway drives pathogenesis of chronic lymphocytic leukemia by the regulation of B-lymphocyte migration
…, M Doubek, A Kozubík, J Mayer, Š Pospíšilová, V Bryja - Cancer research, 2013 - AACR
The planar cell polarity (PCP) pathway is a conserved pathway that regulates cell migration
and polarity in various contexts. Here we show that key PCP pathway components such as …
and polarity in various contexts. Here we show that key PCP pathway components such as …
Purified Wnt‐5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation
G Schulte, V Bryja, N Rawal… - Journal of …, 2005 - Wiley Online Library
The Wnt family of lipoproteins regulates several aspects of the development of the nervous
system. Recently, we reported that Wnt‐3a enhances the proliferation of midbrain …
system. Recently, we reported that Wnt‐3a enhances the proliferation of midbrain …
[HTML][HTML] Breast cancer-specific mutations in CK1ε inhibit Wnt/β-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote …
…, A Kozubík, T Doležal, L Trantírek, V Bryja - Breast Cancer …, 2010 - Springer
Introduction Breast cancer is one of the most common types of cancer in women. One of the
genes that were found mutated in breast cancer is casein kinase 1 epsilon (CK1ε). Because …
genes that were found mutated in breast cancer is casein kinase 1 epsilon (CK1ε). Because …
The interplay of the aryl hydrocarbon receptor and β-catenin alters both AhR-dependent transcription and Wnt/β-catenin signaling in liver progenitors
J Procházková, M Kabátková, V Bryja… - Toxicological …, 2011 - academic.oup.com
β-Catenin is a key integrator of cadherin-mediated cell-cell adhesion and transcriptional
regulation through the Wnt/β-catenin pathway, which plays an important role in liver biology. …
regulation through the Wnt/β-catenin pathway, which plays an important role in liver biology. …
Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism
V Bryja, G Schulte, N Rawal, A Grahn… - Journal of cell …, 2007 - journals.biologists.com
Previously, we have shown that Wnt-5a strongly regulates dopaminergic neuron
differentiation by inducing phosphorylation of Dishevelled (Dvl). Here, we identify additional …
differentiation by inducing phosphorylation of Dishevelled (Dvl). Here, we identify additional …