DNA is stored in vivo in a highly compact, so-called condensed phase, where gene
regulatory processes are governed by the intricate interplay between different states of DNA …

… Teif has been working on DNA-centred biological systems since 1998. A decade later he
entered the nucleosome positioning field, and since then enjoys modelling epigenetic …

We determined genome-wide nucleosome occupancies in mouse embryonic stem cells and
their neural progenitor and embryonic fibroblast counterparts to assess features associated …

During differentiation of embryonic stem cells, chromatin reorganizes to establish cell type-specific
expression programs. Here, we have dissected the linkages between DNA …

Nucleosome positions on the DNA are determined by the intrinsic affinities of histone proteins
to a given DNA sequence and by the ATP-dependent activities of chromatin remodeling …

Coordinated changes of DNA (de)methylation, nucleosome positioning, and chromatin
binding of the architectural protein CTCF play an important role for establishing cell-type–specific …

The nucleosome repeat length (NRL) is an integral chromatin property important for its
biological functions. Recent experiments revealed several conflicting trends of the NRL …

The CCCTC-binding factor (CTCF) organises the genome in 3D through DNA loops and in
1D by setting boundaries isolating different chromatin states, but these processes are not well …

In chronic lymphocytic leukemia ( CLL ), a diverse set of genetic mutations is embedded in a
deregulated epigenetic landscape that drives cancerogenesis. To elucidate the role of …

Nucleosome positioning is involved in many gene regulatory processes happening in the cell,
and it may change as cells differentiate or respond to the changing microenvironment in a …