User profiles for V. K. Ulaganathan
Vijay K. UlaganathanAssociate Professor of Biochemistry & Molecular Biology, @UL and Research Group @UMG Verified email at med.uni-goettingen.de Cited by 715 |
T cells become licensed in the lung to enter the central nervous system
F Odoardi, C Sie, K Streyl, VK Ulaganathan… - Nature, 2012 - nature.com
The blood–brain barrier (BBB) and the environment of the central nervous system (CNS)
guard the nervous tissue from peripheral immune cells. In the autoimmune disease multiple …
guard the nervous tissue from peripheral immune cells. In the autoimmune disease multiple …
Germline variant FGFR4 p. G388R exposes a membrane-proximal STAT3 binding site
VK Ulaganathan, B Sperl, UR Rapp, A Ullrich - Nature, 2015 - nature.com
… Vijay Ulaganathan and colleagues now show that this polymorphic variant, termed
rs351855-G/A, creates a binding site in the FGFR4 protein for the transcription factor STAT3. This in …
rs351855-G/A, creates a binding site in the FGFR4 protein for the transcription factor STAT3. This in …
Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system
…, F Lühder, E Breunig, D Schild, VK Ulaganathan… - Brain, 2010 - academic.oup.com
Nicotinic acid adenine dinucleotide phosphate represents a newly identified second messenger
in T cells involved in antigen receptor-mediated calcium signalling. Its function in vivo is, …
in T cells involved in antigen receptor-mediated calcium signalling. Its function in vivo is, …
[HTML][HTML] STAT3-enhancing germline mutations contribute to tumor-extrinsic immune evasion
Immune evasion and the suppression of antitumor responses during cancer progression
are considered hallmarks of cancer and are typically attributed to tumor-derived factors. …
are considered hallmarks of cancer and are typically attributed to tumor-derived factors. …
Neo-epitope tissue transglutaminase autoantibodies as a biomarker of the gluten sensitive skin disease—Dermatitis herpetiformis
…, A Szaflarska-Poplawska, VK Ulaganathan… - Clinica Chimica …, 2013 - Elsevier
BACKGROUND: The deamidated gliadin peptides (DGP) cross linked to human tissue
transglutaminase (tTg) comprises a novel neo-epitope structure (Neo-tTg) for serological …
transglutaminase (tTg) comprises a novel neo-epitope structure (Neo-tTg) for serological …
[HTML][HTML] Sequential salinomycin treatment results in resistance formation through clonal selection of epithelial-like tumor cells
Acquiring therapy resistance is one of the major obstacles in the treatment of patients with
cancer. The discovery of the cancer stem cell (CSC)–specific drug salinomycin raised hope for …
cancer. The discovery of the cancer stem cell (CSC)–specific drug salinomycin raised hope for …
A strategy for uncovering germline variants altering anti-tumor CD8 T cell response
VK Ulaganathan, MH Vasileva - Journal of Genetics and Genomics, 2023 - Elsevier
… anesthesia, immunization, and euthanasia by cervical dislocation, were carried out by
trained and licensed personnel (File numbers: 33.9-42502-14-Mole and T20/8-Ulaganathan) in …
trained and licensed personnel (File numbers: 33.9-42502-14-Mole and T20/8-Ulaganathan) in …
Membrane-proximal binding of STAT3 revealed by cancer-associated receptor variants
VK Ulaganathan, A Ullrich - Molecular & Cellular Oncology, 2016 - Taylor & Francis
In cancer biology, somatic mutations in the extracellular (ligand binding) and cytosolic (functional/catalytic)
domains are pursued with great interest. However, in our recent publication …
domains are pursued with great interest. However, in our recent publication …
Membrane Anchorage‐Induced (MAGIC) Knockdown of Non‐synonymous Point Mutations
VK Ulaganathan - ChemBioChem, 2022 - Wiley Online Library
The promise of personalized medicine for monogenic and complex polygenic diseases
depends on the availability of strategies for targeted inhibition of disease‐associated …
depends on the availability of strategies for targeted inhibition of disease‐associated …
[HTML][HTML] TraPS-VarI: Identifying genetic variants altering phosphotyrosine based signalling motifs
VK Ulaganathan - Scientific Reports, 2020 - nature.com
Patient stratification and individualized therapeutic strategies rely on the established
knowledge of genotype-specific molecular and cellular alterations of biological and therapeutic …
knowledge of genotype-specific molecular and cellular alterations of biological and therapeutic …