Eukaryotic genomes contain a variety of structured patterns: repetitive elements, binding
sites of DNA and RNA associated proteins, splice sites, and so on. Often, these structured …

Liver transplantation is the current standard of care for end-stage liver disease and an accepted
therapeutic option for acute liver failure and primary liver tumors. Despite the remarkable …

More and more cancer studies use next-generation sequencing (NGS) data to detect various
types of genomic variation. However, even when researchers have such data at hand, …

Due to the need for improvement in the diagnosis and minimally invasive therapy of the bile
duct disorders new technologies for cholangioscopy have been recently developed. Per-oral …

Neuroblastoma is a tumor of the peripheral sympathetic nervous system 1 , derived from
multipotent neural crest cells (NCCs). To define core regulatory circuitries (CRCs) controlling …

The methods of synthesis and the properties of polyaniline—a representative of the family of
conducting polymers—are reviewed briefly. It is shown that variation in the conditions of …

We present a tool for control-free copy number alteration (CNA) detection using deep-sequencing
data, particularly useful for cancer studies. The tool deals with two frequent problems …

We present SVDetect, a program designed to identify genomic structural variations from
paired-end and mate-pair next-generation sequencing data produced by the Illumina GA and …

During X chromosome inactivation (XCI), the Polycomb Repressive Complex 2 (PRC2) is
thought to participate in the early maintenance of the inactive state. Although Xist RNA is …

Importance There is limited evidence on the benefits of sacubitril/valsartan vs broader renin
angiotensin system inhibitor background therapy on surrogate outcome markers, 6-minute …