Consomic (chromosome substitution) strains (CSs) represent the most recent addition to the
mouse genetic resources aimed to geneticaly analyze complex trait loci (QTLs). In this study…

10.7554/eLife.34282.001 Hybrid sterility is one of the reproductive isolation mechanisms
leading to speciation. Prdm9, the only known vertebrate hybrid-sterility gene, causes failure of …

Meiotic recombination safeguards proper segregation of homologous chromosomes into
gametes, affects genetic variation within species, and contributes to meiotic chromosome …

The classical definition posits hybrid sterility as a phenomenon when two parental taxa each
of which is fertile produce a hybrid that is sterile. The first hybrid sterility gene in vertebrates, …

A novel penicillin G acylase from the bacterial strain Achromobacter sp. CCM 4824 was
characterized. The specific activity of purified enzyme was 27.6Umg −1 protein (6-nitro-3-…

Extensive linkage disequilibrium among classical laboratory strains represents an obstacle
in the high-resolution haplotype mapping of mouse quantitative trait loci (QTL). To determine …

The infertility of hybrids between closely related (sub)species is one of the early reproductive
isolation mechanisms leading to speciation. Since the genetic control of hybrid sterility (HS) …

Hybrid sterility contributes to speciation by preventing gene flow between related taxa. Prdm9,
the first and only hybrid male sterility gene known in vertebrates, predetermines the sites …

Hybrid sterility as a postzygotic reproductive isolation mechanism has been studied for over
80 years, yet the first identifications of hybrid sterility genes in Drosophila and mouse are …