[HTML][HTML] X chromosome control of meiotic chromosome synapsis in mouse inter-subspecific hybrids

…, R Reifova, S Gregorova, P Simecek, V Gergelits… - PLoS …, 2014 - journals.plos.org
Hybrid sterility (HS) belongs to reproductive isolation barriers that safeguard the integrity of
species in statu nascendi. Although hybrid sterility occurs almost universally among animal …

Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice

S Gregorova, V Gergelits, I Chvatalova… - Elife, 2018 - elifesciences.org
10.7554/eLife.34282.001 Hybrid sterility is one of the reproductive isolation mechanisms
leading to speciation. Prdm9, the only known vertebrate hybrid-sterility gene, causes failure of …

[HTML][HTML] AutoSpill is a principled framework that simplifies the analysis of multichromatic flow cytometry data

CP Roca, OT Burton, V Gergelits, T Prezzemolo… - Nature …, 2021 - nature.com
Compensating in flow cytometry is an unavoidable challenge in the data analysis of
fluorescence-based flow cytometry. Even the advent of spectral cytometry cannot circumvent the …

[HTML][HTML] Hybrid sterility locus on chromosome X controls meiotic recombination rate in mouse

M Balcova, B Faltusova, V Gergelits… - PLoS …, 2016 - journals.plos.org
Meiotic recombination safeguards proper segregation of homologous chromosomes into
gametes, affects genetic variation within species, and contributes to meiotic chromosome …

Laplacian preconditioning of elliptic PDEs: Localization of the eigenvalues of the discretized operator

T Gergelits, KA Mardal, BF Nielsen, Z Strakos - SIAM Journal on Numerical …, 2019 - SIAM
In [IMA J. Numer. Anal., 29 (2009), pp. 24--42], Nielsen, Tveito, and Hackbusch study the
operator generated by using the inverse of the Laplacian as the preconditioner for second order …

Composite convergence bounds based on Chebyshev polynomials and finite precision conjugate gradient computations

T Gergelits, Z Strakoš - Numerical Algorithms, 2014 - Springer
The conjugate gradient method (CG) for solving linear systems of algebraic equations
represents a highly nonlinear finite process. Since the original paper of Hestenes and Stiefel …

Unstable regulatory T cells, enriched for naïve and Nrp1neg cells, are purged after fate challenge

…, F Staels, V Malviya, O Burton, V Gergelits… - Science …, 2021 - science.org
Regulatory T cells (T regs ) are indispensable for the control of immune homeostasis and have
clinical potential as a cell therapy for treating autoimmunity. T regs can lose expression of …

Genomic Structure of Hstx2 Modifier of Prdm9-Dependent Hybrid Male Sterility in Mice

…, KK Ullrich, M Yancoskie, L Kašíková, V Gergelits… - Genetics, 2019 - academic.oup.com
F 1 hybrids between mouse inbred strains PWD and C57BL/6 represent the most thoroughly
genetically defined model of hybrid sterility in vertebrates. Hybrid male sterility can be fully …

Mixed precision s‐step Lanczos and conjugate gradient algorithms

E Carson, T Gergelits, I Yamazaki - Numerical Linear Algebra …, 2022 - Wiley Online Library
Compared to the classical Lanczos algorithm, the s‐step Lanczos variant has the potential
to improve performance by asymptotically decreasing the synchronization cost per iteration. …

[PDF][PDF] A cross entropy test allows quantitative statistical comparison of t-SNE and UMAP representations

…, J Neumann, S Tareen, CE Whyte, V Gergelits… - Cell Reports …, 2023 - cell.com
The advent of high-dimensional single-cell data has necessitated the development of
dimensionality-reduction tools. t-Distributed stochastic neighbor embedding (t-SNE) and uniform …