Tackling antibiotic resistance: the environmental framework
…, P Huovinen, S Stefani, T Schwartz, V Kisand… - Nature reviews …, 2015 - nature.com
Antibiotic resistance is a threat to human and animal health worldwide, and key measures
are required to reduce the risks posed by antibiotic resistance genes that occur in the …
are required to reduce the risks posed by antibiotic resistance genes that occur in the …
[HTML][HTML] Environmental DNA metabarcoding for benthic monitoring: A review of sediment sampling and DNA extraction methods
Environmental DNA (eDNA) metabarcoding (parallel sequencing of DNA/RNA for identification
of whole communities within a targeted group) is revolutionizing the field of aquatic …
of whole communities within a targeted group) is revolutionizing the field of aquatic …
[HTML][HTML] Lake sedimentary DNA research on past terrestrial and aquatic biodiversity: Overview and recommendations
The use of lake sedimentary DNA to track the long-term changes in both terrestrial and aquatic
biota is a rapidly advancing field in paleoecological research. Although largely applied …
biota is a rapidly advancing field in paleoecological research. Although largely applied …
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
…, JS Tsang, R Goldbach-Mansky, K Kisand… - Science, 2020 - science.org
INTRODUCTION Interindividual clinical variability is vast in humans infected with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranging from silent infection to rapid …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranging from silent infection to rapid …
[HTML][HTML] A dynamic COVID-19 immune signature includes associations with poor prognosis
Improved understanding and management of COVID-19, a potentially life-threatening disease,
could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward this end…
could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward this end…
[HTML][HTML] Dynamics of antibody response to BNT162b2 vaccine after six months: a longitudinal prospective study
Background SARS-CoV-2 mRNA vaccines have proven high efficacy, however, limited data
exists on the duration of immune responses and their relation to age and side effects. …
exists on the duration of immune responses and their relation to age and side effects. …
Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines
K Kisand, AS Bøe Wolff, KT Podkrajšek… - Journal of Experimental …, 2010 - rupress.org
Chronic mucocutaneous candidiasis (CMC) is frequently associated with T cell immunodeficiencies.
Specifically, the proinflammatory IL-17A–producing Th17 subset is implicated in …
Specifically, the proinflammatory IL-17A–producing Th17 subset is implicated in …
[HTML][HTML] Size-Dependent Toxicity of Silver Nanoparticles to Bacteria, Yeast, Algae, Crustaceans and Mammalian Cells In Vitro
The concept of nanotechnologies is based on size-dependent properties of particles in the 1–100
nm range. However, the relation between the particle size and biological effects is still …
nm range. However, the relation between the particle size and biological effects is still …
[HTML][HTML] Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1
…, T Battelino, K Trebušak Podkrajšek, K Kisand… - Journal of Experimental …, 2021 - rupress.org
Disclosures: PD Burbelo reported US Patent no. 10,564,152 issued. JC Casanova reported
a patent to 63/055,155 pending and a patent to 63/141,669 pending. No other disclosures …
a patent to 63/055,155 pending and a patent to 63/141,669 pending. No other disclosures …
Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype
Since their discovery in patients with autosomal dominant (AD) chronic mucocutaneous
candidiasis (CMC) in 2011, heterozygous STAT1 gain-of-function (GOF) mutations have …
candidiasis (CMC) in 2011, heterozygous STAT1 gain-of-function (GOF) mutations have …