The prevalence and incidence of type 2 diabetes, representing. 90% of all cases of diabetes,
are increasing rapidly throughout the world. The International Diabetes Federation has …

Objectives Given the complex demands of many workplaces, there is growing interest in the
potential beneficial effects of mindfulness-based programs (MBPs) for employees. This meta-…

Melatonin is a circulating hormone that is primarily released from the pineal gland. It is best
known as a regulator of seasonal and circadian rhythms; its levels are high during the night …

New strategies for prevention and treatment of type 2 diabetes (T2D) require improved insight
into disease etiology. We analyzed 386,731 common single-nucleotide polymorphisms (…

Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …

Genome-wide association (GWA) studies have identified multiple loci at which common variants
modestly but reproducibly influence risk of type 2 diabetes (T2D) 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , …

By combining genome-wide association data from 8,130 individuals with type 2 diabetes (T2D)
and 38,987 controls of European descent and following up previously unidentified meta-…

Transcription factor-7–like 2 (TCF7L2) is the most important type 2 diabetes susceptibility
gene identified to date, with common intronic variants strongly associated with diabetes in all …

We expanded GWAS discovery for type 2 diabetes (T2D) by combining data from 898,130
European-descent individuals (9% cases), after imputation to high-density reference panels. …

Background Type 2 diabetes mellitus is thought to develop from an interaction between
environmental and genetic factors. We examined whether clinical or genetic factors or both could …