[HTML][HTML] Structural perspective of cooperative transcription factor binding

E Morgunova, J Taipale - Current opinion in structural biology, 2017 - Elsevier
Highlights • Transcription factors can cooperate with each other via multiple mechanisms
that have different specificities and ranges. • Cooperativity can result from direct protein–protein …

[HTML][HTML] Russian natural gas exports: An analysis of challenges and opportunities

V Kutcherov, M Morgunova, V Bessel, A Lopatin - Energy Strategy Reviews, 2020 - Elsevier
This study provides a comprehensive, updated, and refined analysis of the challenges and
opportunities for Russian natural gas exports based on recent statistical data, academic …

[HTML][HTML] DNA-binding specificities of human transcription factors

…, J Toivonen, KR Nitta, P Rastas, E Morgunova… - Cell, 2013 - cell.com
Although the proteins that read the gene regulatory code, transcription factors (TFs), have
been largely identified, it is not well known which sequences TFs can recognize. We have …

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Y Yin, E Morgunova, A Jolma, E Kaasinen, B Sahu… - Science, 2017 - science.org
INTRODUCTION Nearly all cells in the human body share the same primary genome sequence
consisting of four nucleotide bases. One of the bases, cytosine, is commonly modified by …

Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed

E Morgunova, A Tuuttila, U Bergmann, M Isupov… - Science, 1999 - science.org
Matrix metalloproteinases (MMPs) catalyze extracellular matrix degradation. Control of their
activity is a promising target for therapy of diseases characterized by abnormal connective …

[HTML][HTML] The origins and spread of domestic horses from the Western Eurasian steppes

…, R Zhumatayev, A Toleubaev, NL Morgunova… - Nature, 2021 - nature.com
Domestication of horses fundamentally transformed long-range mobility and warfare 1 .
However, modern domesticated breeds do not descend from the earliest domestic horse lineage …

DNA-dependent formation of transcription factor pairs alters their binding specificity

…, A Popov, M Taipale, M Enge, T Kivioja, E Morgunova… - Nature, 2015 - nature.com
Gene expression is regulated by transcription factors (TFs), proteins that recognize short DNA
sequence motifs 1 , 2 , 3 . Such sequences are very common in the human genome, and …

Successive deposition of alternate layers of polyelectrolytes and a charged virus

…, A Mikhailov, B Mtchedlishvily, E Morgunova… - Langmuir, 1994 - ACS Publications
Densely packed monolayers of a charged virus are sandwiched in multilayer films of charged
polyelectrolytes by successive adsorption of molecules of opposite charges. By small-…

The interaction landscape between transcription factors and the nucleosome

…, Y Yin, B Wei, SO Dodonova, KR Nitta, E Morgunova… - Nature, 2018 - nature.com
Nucleosomes cover most of the genome and are thought to be displaced by transcription
factors in regions that direct gene expression. However, the modes of interaction between …

Structural insight into the complex formation of latent matrix metalloproteinase 2 with tissue inhibitor of metalloproteinase 2

E Morgunova, A Tuuttila… - Proceedings of the …, 2002 - National Acad Sciences
Matrix metalloproteinases (MMPs) are a family of multidomain enzymes involved in the
physiological degradation of connective tissue, as well as in pathological states such as tumor …