In multicellular organisms, communication between cells mainly involves the secretion of
proteins that then bind to receptors on neighbouring cells. But another mode of intercellular …

The presentation of exogenous antigens on MHC class I molecules, known as cross-presentation,
is essential for the initiation of CD8 + T cell responses. In vivo, cross-presentation is …

The mononuclear phagocyte system (MPS) has historically been categorized into monocytes,
dendritic cells and macrophages on the basis of functional and phenotypical characteristics…

Population structure causes genome-wide linkage disequilibrium between unlinked loci,
leading to statistical confounding in genome-wide association studies. Mixed models have …

The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB),
the US data center for the global PDB archive and a founding member of the Worldwide …

Software product line engineering is about producing a set of related products that share
more commonalities than variabilities. Feature models are widely used for variability and …

Cellular senescence is a permanent state of cell cycle arrest that promotes tissue
remodeling during development and after injury, but can also contribute to the decline of the …

Objective The coronavirus disease 2019 (COVID-19) has spread worldwide since December
2019. Neurologic symptoms have been reported as part of the clinical spectrum of the …

The gastrointestinal peptide hormone ghrelin stimulates appetite in rodents and humans via
hypothalamic actions. We discovered expression of ghrelin in a previously uncharacterized …

Vessel sprouting by migrating tip and proliferating stalk endothelial cells (ECs) is controlled
by genetic signals (such as Notch), but it is unknown whether metabolism also regulates this …