Autophagy is emerging as a core regulator of Central Nervous System (CNS) aging and
neurodegeneration. In the brain, it has mostly been studied in neurons, where the delivery of …

During adult hippocampal neurogenesis, most newborn cells undergo apoptosis and are
rapidly phagocytosed by resident microglia to prevent the spillover of intracellular contents. …

Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neurons
and inflammatory responses. Whereas microglia are very competent phagocytes under …

Autophagy is a complex process that encompasses the enclosure of cytoplasmic debris or
dysfunctional organelles in membranous vesicles, the autophagosomes, for their elimination …

Objective Microglial phagocytosis of apoptotic cells is an essential component of the brain
regenerative response during neurodegeneration. Whereas it is very efficient in physiological …

The SARS-CoV-2 pandemic has evolved far more aggressively in countries lacking a robust
testing strategy to identify infected individuals. Given the global demand for fast and reliable …

Background and aims Central line-associated bloodstream infections (CLABSIs) are the main
complication in children with home parenteral nutrition (HPN) and some patients develop …

Lysosomal digestion in microglia includes intracellular cargo recycling by autophagy and
extracellular substrate clearance by phagocytosis. Microglia are the brain resident …

Microglial phagocytosis of apoptotic cells is an essential component of the brain regenerative
response in neurodegenerative diseases. Phagocytosis is very efficient in physiological …

Microglial phagocytosis is rapidly emerging as a therapeutic target in neurodegenerative
and neurological disorders. An efficient removal of cellular debris is necessary to prevent …