T cell immunity is central for the control of viral infections. To characterize T cell immunity,
but also for the development of vaccines, identification of exact viral T cell epitopes is …

Immunotherapy is revolutionizing cancer treatment and has shown success in particular for
tumors with a high mutational load. These effects have been linked to neoantigens derived …

Basic region leucine zipper (bZIP) transcription factors of the TGA family control gene
expression in response to diverse stimuli. Arabidopsis clade II and clade III TGA factors mediate …

The SARS-CoV-2 pandemic calls for the rapid development of diagnostic, preventive, and
therapeutic approaches. CD4+ and CD8+ T cell-mediated immunity is central for control of …

Translation from immunopeptidomics to HLA peptide target to TCR lead to cancer
immunotherapy. Cancer antigen Ag007-01 (blue) bound to HLA-A* 02: 01 (red) recognized by …

Personalized cancer immunotherapy targeting patient-specific cancer/testis antigens (CTA)
and neoantigens may benefit from large-scale tumor human leukocyte antigen (HLA) …

NONEXPRESSOR OF PATHOGENESIS-RELATED (PR) GENES1 (NPR1) is the central
regulator of salicylic acid (SA)-induced PR-1 gene expression and systemic acquired resistance …

Glioblastoma multiforme (GBM) is the most aggressive brain tumor with poor prognosis to
most patients. Immunotherapy of GBM is a potentially beneficial treatment option, whose …

Genetic studies have demonstrated that NPR1 is the key positive regulator of salicylic acid (SA)-induced
PR-1 gene induction and systemic acquired resistance (SAR). In Arabidopsis, …

Peptides presented at the cell surface reflect the protein content of the cell; those on HLA class
I molecules comprise the critical peptidome elements interacting with CD8 T lymphocytes. …