The EcoCyc model-organism database collects and summarizes experimental data for
Escherichia coli K-12. EcoCyc is regularly updated by the manual curation of individual database …

Genomics has set the basis for a variety of methodologies that produce high-throughput
datasets identifying the different players that define gene regulation, particularly regulation of …

Background Our understanding of the regulation of gene expression has benefited from the
availability of high-throughput technologies that interrogate the whole genome for the …

In free-living bacteria, the ability to regulate gene expression is at the core of adapting and
interacting with the environment. For these systems to have a logic, a signal must trigger a …

Ferrioxamines‐mediated iron acquisition by Streptomyces coelicolor A3(2) has recently
received increased attention. In addition to the biological role of desferrioxamines (dFOs) as …

In the genus Streptomyces, carbon utilization is of significant importance for the expression
of genes involved in morphological differentiation and antibiotic production. However, there …

Background The ability to express the same meaning in different ways is a well-known
property of natural language. This amazing property is the source of major difficulties in natural …

Post-genomic implementations have expanded the experimental strategies to identify elements
involved in the regulation of transcription initiation. Here, we present for the first time a …

The labdane-related diterpenoids (LRDs) are a large group of natural products with a broad
range of biological activities. They are synthesized through two consecutive reactions …

Motivation A major component in increasing our understanding of the biology of an organism
is the mapping of its genotypic potential into its phenotypic expression profiles. This …