Plants with genetically encoded autoluminescence

…, AS Tsarkova, YV Golubev, VV Negrebetsky… - Nature …, 2020 - nature.com
Autoluminescent plants engineered to express a bacterial bioluminescence gene cluster in
plastids have not been widely adopted because of low light output. We engineered tobacco …

[HTML][HTML] A novel phenylpyrrolidine derivative: synthesis and effect on cognitive functions in rats with experimental ishemic stroke

…, AD Shagina, NM Kiseleva, VV Negrebetsky… - Molecules, 2021 - mdpi.com
We performed an in silico, in vitro, and in vivo assessment of a potassium 2-[2-(2-oxo-4-phenylpyrrolidin-1-yl)
acetamido]ethanesulfonate (compound 1) as a potential prodrug for …

Phospholipidic colchicinoids as promising prodrugs incorporated into enzyme-responsive liposomes: chemical, biophysical, and enzymological aspects

…, EV Svirshchevskaya, VV Negrebetsky… - Bioconjugate …, 2019 - ACS Publications
Enzyme-responsive liposomes release their cargo in response to pathologically increased
levels of enzymes at the target site. We report herein an assembly of phospholipase A2-…

Synthesis, structures, and stereodynamic behavior of novel pentacoordinate fluorosilanes: fluorosilyl derivatives of proline

…, AG Shipov, YI Baukov, VV Negrebetsky… - …, 2012 - ACS Publications
The (O→Si)-chelate N′-(dimethylfluorosilylmethyl))-N′-methyl-N-(organosulfonyl)prolinamides
RSO 2 -Pro-N(Me)CH 2 SiMe 2 F (2a–f, R = Me (a), Ph (b), 4-MeC 6 H 4 (c), 4-ClC 6 H …

(Amidomethyl) dimethylsilanol hydrohalides: Synthesis, NMR and IR studies. Characteristic features of the electronic structure from high-resolution X-ray study and …

…, EP Kramarova, VV Negrebetsky… - Journal of …, 2006 - Elsevier
(C,O)-chelate silanol hydrohalides RC(O)NHCH 2 SiMe 2 OH·HHal (2a,b and 5b), and their
precursors, (C,O)-chelate chlorosilanes RC(O)NHCH 2 SiMe 2 Cl (6a,b) and disiloxanes [RC…

Synthesis, properties and reactivity of intramolecular hypercoordinate silicon complexes

AA Nikolin, VV Negrebetsky - Russian Chemical Reviews, 2014 - iopscience.iop.org
The state of the art of the chemistry of hypercoordinate silicon compounds is analyzed.
Published data on the current top-priority approaches to the preparative synthesis of these …

[HTML][HTML] The Effect of a New N-hetero Cycle Derivative on Behavior and Inflammation against the Background of Ischemic Stroke

…, AA Chernysheva, NM Kiseleva, VV Negrebetsky… - Molecules, 2022 - mdpi.com
Ischemic stroke triggers a whole cascade of pathological changes in the brain, one of which
is postischemic inflammation. Since in such cases thrombolytic therapy is often not possible, …

[HTML][HTML] Pyridine Carboxamides Based on Sulfobetaines: Design, Reactivity, and Biological Activity

…, TA Shmigol, YI Baukov, VV Negrebetsky - Molecules, 2022 - mdpi.com
The synthesis of the products of the 1,3-propanesultone ring opening during its interaction
with amides of pyridinecarboxylic acids has been carried out. The dependence of the yield of …

[HTML][HTML] N, N-Bis-(dimethylfluorosilylmethyl) amides of N-organosulfonylproline and sarcosine: synthesis, structure, stereodynamic behaviour and in silico studies

…, AG Shipov, YI Baukov, VV Negrebetsky… - RSC …, 2016 - pubs.rsc.org
… CAS; (e) AA Korlyukov, KA Lyssenko, MY Antipin, AG Shipov, OA Zamyshlyaeva, EP
Kramarova, VV Negrebetsky, SA Pogozhikh, YE Ovchinnikov and YI Baukov, Russ. Chem. Bull., …

Synthesis, structure and dynamic stereochemistry of (O→ Si)-chelate N-(trifluorosilylmethyl)-[N-(S)-(1-phenylethyl)] acetamide and 1-(trifluorosilylmethyl)-2 …

VV Negrebetsky, PG Taylor, EP Kramarova… - Journal of …, 2008 - Elsevier
The novel compounds, N-(trifluorosilylmethyl)-[N-(S)-(1-phenylethyl)]-acetamide (1a) and 1-(trifluorosilylmethyl)-2-oxoperhydroazepine
(1b) have been prepared from the corresponding …