Mass spectrometry (MS) is by far the most used experimental approach in high-throughput
proteomics. The ProteomeXchange (PX) consortium of proteomics resources ( http://www.…

The senescence-associated secretory phenotype (SASP) has recently emerged as a driver
of and promising therapeutic target for multiple age-related conditions, ranging from …

The ProteomeXchange (PX) consortium of proteomics resources ( http://www.proteomexchange.org
) has standardized data submission and dissemination of mass spectrometry …

Vendor-independent software tools for quantification of small molecules and metabolites
are lacking, especially for targeted analysis workflows. Skyline is a freely available, open-…

Panorama is a web application for storing, sharing, analyzing, and reusing targeted assays
created and refined with Skyline,1 an increasingly popular Windows client software tool for …

To address the growing need for a centralized, community resource of published results
processed with Skyline, and to provide reviewers and readers immediate visual access to the …

To the Editor: A growing trend in protein quantification is a targeted mass spectrometry (MS)-based
technology called multiple reaction monitoring (MRM) or selected reaction monitoring …

Although the value of proteomics has been demonstrated, cost and scale are typically prohibitive,
and gene expression profiling remains dominant for characterizing cellular responses …

We report the development of a completely automated pipeline to monitor system suitability
in bottom-up proteomic experiments. LC–MS/MS runs are automatically imported into …

Background Quantitative proteomics holds great promise for identifying proteins that are
differentially abundant between populations representing different physiological or disease …