Here we present a guide to ion mobility mass spectrometry experiments, which covers both
linear and nonlinear methods: what is measured, how the measurements are done, and how …

We report systematic investigation of duplex DNA complexes with minor groove binders (Hoechsts
33258 and 33342, netropsin and DAPI) and intercalators (daunomycin, doxorubicin, …

Highlights • CCS distributions and shifts contain valuable information about analytes. •
Compound-dependent effects of gas, field and temperature explain calibration issues. • New …

G-rich DNA sequences are able to fold into structures called G-quadruplexes. To obtain
general trends in the influence of loop length on the structure and stability of G-quadruplex …

DNA triplex and quadruplex structures have been successfully detected by electrospray
ionization mass spectrometry (ESI‐MS). Circular dichroism and UV‐melting experiments show …

We present here a tutorial review on the electrospray mass spectrometry technique and its
applications to the study of drug-nucleic acid non-covalent complexes. Particular emphasis …

Nucleic acids have been among the first targets for antitumor drugs and antibiotics. With the
unveiling of new biological roles in regulation of gene expression, specific DNA and RNA …

We report here the details of G4-FID (G-quadruplex fluorescent intercalator displacement), a
simple method aiming at evaluating quadruplex-DNA binding affinity and quadruplex- over …

Proteins are complex macromolecules that evolved over billions of years to be active in
aqueous solution. Water is a key element that stabilizes their structure, and most structural …

This review addresses the determination of the internal energy of ions produced by
electrospray ionization (ESI) sources, and the influence of the internal energy on analyte …