[HTML][HTML] Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy

…, A Wiederkehr, A Sinopoli, V Do Sacramento… - Journal of Experimental …, 2023 - rupress.org
Targeted eradication of transformed or otherwise dysregulated cells using monoclonal
antibodies (mAb), antibody–drug conjugates (ADC), T cell engagers (TCE), or chimeric antigen …

[HTML][HTML] Development of an efficient, ready to use, blood platelet-release device based on two new flow regime parameters: The periodic hydrodynamic loading and …

A Pongérard, L Mallo, V Do Sacramento, O Boiron… - New …, 2023 - Elsevier
In vitro production of blood platelets for transfusion purposes is gaining interest. While
platelet production is now possible on a laboratory scale, the challenge is to move towards …

[HTML][HTML] Functional properties of human platelets derived in vitro from CD34+ cells

V Do Sacramento, L Mallo, M Freund, A Eckly… - Scientific reports, 2020 - nature.com
The in vitro production of blood platelets for transfusion purposes is an important goal in the
context of a sustained demand for controlled products free of infectious, immune and …

Engineered Single Amino Acid Substitutions Protect Hematopoietic Stem and Progenitor Cells from CD123 Targeted Immunotherapy

…, LC Wellinger, A Sinopoli, V Do Sacramento… - Blood, 2022 - ashpublications.org
Targeted eradication of transformed or otherwise dysregulated cells using monoclonal
antibodies (mAb), T cell engagers (TCE) or chimeric antigen receptor (CAR) cells is very effective …

Function-Preserving Single Amino Acid Substitutions Shield Hematopoietic Stem and Progenitor Cells from CD117 Targeted Immunotherapy In Vivo

…, A Knezevic, FM Lehmann, V Do Sacramento… - Blood, 2022 - ashpublications.org
Current untargeted cytotoxic conditioning regimens for hematopoietic stem cell transplantation
(HSCT) have been directly or indirectly associated with transplant related morbidity and …

[HTML][HTML] AHR: IKAROS interaction promotes platelet biogenesis in response to SR1

L Mallo, V Do Sacramento, C Gachet, S Chan… - Reports, 2021 - mdpi.com
In vitro, the differentiation of megakaryocytes (MKs) is improved by aryl-hydrocarbon receptor
(AHR) antagonists such as StemRegenin 1 (SR1), an effect physiologically recapitulated …

Transcriptome analysis of the effect of AHR on productive and unproductive pathways of in vitro megakaryocytopoiesis

L Mallo, VD Sacramento, C Gachet, F Lanza… - bioRxiv, 2021 - biorxiv.org
Human CD34 + progenitors can be differentiated in vitro into proplatelet-producing megakaryocytes
(MKs) within 17 days. During this time, four cell populations emerge, phenotypically …

[PDF][PDF] Oral history interview with Xochilt Quetzal Juarez

JBA Valentin, XQ Juarez - scholars.csus.edu
… Today, September 5, 2023 and we are in Mendocino hall 3013 and we are on the campus
of Sacramento State. We will be recording an oral history of Professor Gow Fall 2023 and …

Public opinion as an indicator of the social sustainability of construction projects

V Valentin, SM Bogus - ICSDEC 2012: Developing the Frontier of …, 2013 - ascelibrary.org
… The program includes the possible construction of a canal or tunnel to move water around
the Sacramento-San Joaquin, water conveyance systems, among other components. The …

[PDF][PDF] Oral history interview with Jeron Valentin

JBA Valentin, JVA Palagud - scholars.csus.edu
… Today is the 5th of September 2023 and we are currently in Mendocino Hall at room 13 here
at the University of Sacramento State, California. … So is squats like your favorite workout to do …