While the number of human miRNA candidates continuously increases, only a few of them
are completely characterized and experimentally validated. Toward determining the total …

The study of bacterial isolates or communities requires the analysis of the therein included
plasmids in order to provide an extensive characterization of the organisms. Plasmids …

Background Pathogenic microorganisms cause disease by invading, colonizing, and
damaging their host. Virulence factors including bacterial toxins contribute to pathogenicity. …

Importance The overall low survival rate of patients with lung cancer calls for improved
detection tools to enable better treatment options and improved patient outcomes. Multivariable …

Background miRNA profiles are promising biomarker candidates for a manifold of human
pathologies, opening new avenues for diagnosis and prognosis. Beyond studies that describe …

Metagenomics-based studies of mixed microbial communities are impacting biotechnology,
life sciences and medicine. Computational binning of metagenomic data is a powerful …

Validation of biomarkers is essential to advance the translational process to clinical
application. Although there exists an increasing number of reports on small non-coding RNAs (…

The composition of the gut microbiota is linked to multiple diseases, including Parkinson’s
disease (PD). Abundance of bacteria producing short-chain fatty acids (SCFAs) and fecal …

Small non-coding RNAs play a key role in many physiological and pathological processes.
Since 2004, miRNA sequences have been catalogued in miRBase, which is currently in its …

Introduction Molecular biomarkers for Alzheimer's disease (AD) can support detection and
improved care for patients, but novel candidates require verification. We previously reported a …