User profiles for Valentinos Zachariou

Valentinos Zachariou

Assistant Professor, Department of Neuroscience, University of Kentucky
Verified email at uky.edu
Cited by 424

Ventral and dorsal visual stream contributions to the perception of object shape and object location

V Zachariou, R Klatzky, M Behrmann - Journal of Cognitive …, 2014 - direct.mit.edu
Growing evidence suggests that the functional specialization of the two cortical visual pathways
may not be as distinct as originally proposed. Here, we explore possible contributions of …

Instrumental validation of free water, peak‐width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits

…, BT Gold, CE Bauer, V Zachariou… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction To describe the protocol and findings of the instrumental validation of three
imaging‐based biomarker kits selected by the MarkVCID consortium: free water (FW) and peak …

[PDF][PDF] Spatial mechanisms within the dorsal visual pathway contribute to the configural processing of faces

V Zachariou, CV Nikas, ZN Safiullah, SJ Gotts… - Cerebral …, 2017 - academic.oup.com
Human face recognition is often attributed to configural processing; namely, processing the
spatial relationships among the features of a face. If configural processing depends on fine-…

Evaluation of multi-echo ICA denoising for task based fMRI studies: Block designs, rapid event-related designs, and cardiac-gated fMRI

…, DA Handwerker, DC Jangraw, V Zachariou… - Neuroimage, 2016 - Elsevier
Multi-echo fMRI, particularly the multi-echo independent component analysis (ME-ICA)
algorithm, has previously proven useful for increasing the sensitivity and reducing false positives …

[HTML][HTML] Bottom-up processing of curvilinear visual features is sufficient for animate/inanimate object categorization

V Zachariou, AC Del Giacco, LG Ungerleider… - Journal of …, 2018 - iovs.arvojournals.org
Animate and inanimate objects differ in their intermediate visual features. For instance, animate
objects tend to be more curvilinear compared to inanimate objects (eg, Levin, Takarae, …

[HTML][HTML] White matter hyperintensity volume and location: associations with WM microstructure, brain iron, and cerebral perfusion

CE Bauer, V Zachariou, E Seago… - Frontiers in aging …, 2021 - frontiersin.org
Cerebral white matter hyperintensities (WMHs) represent macrostructural brain damage
associated with various etiologies. However, the relative contributions of various etiologies to …

Size precedes view: developmental emergence of invariant object representations in lateral occipital complex

M Nishimura, KS Scherf, V Zachariou… - Journal of cognitive …, 2015 - direct.mit.edu
Although object perception involves encoding a wide variety of object properties (eg, size,
color, viewpoint), some properties are irrelevant for identifying the object. The key to …

High cortical iron is associated with the disruption of white matter tracts supporting cognitive function in healthy older adults

V Zachariou, CE Bauer, C Pappas, BT Gold - Cerebral Cortex, 2023 - academic.oup.com
Aging is associated with brain iron accumulation, which has been linked to cognitive decline.
However, how brain iron affects the structure and function of cognitive brain networks …

[HTML][HTML] Ironsmith: an automated pipeline for QSM-based data analyses

V Zachariou, CE Bauer, DK Powell, BT Gold - Neuroimage, 2022 - Elsevier
Quantitative susceptibility mapping (QSM) is an MRI-based, computational method for
anatomically localizing and measuring concentrations of specific biomarkers in tissue such as iron…

[HTML][HTML] Cortical iron disrupts functional connectivity networks supporting working memory performance in older adults

V Zachariou, CE Bauer, ER Seago, FD Raslau… - NeuroImage, 2020 - Elsevier
Excessive brain iron negatively affects working memory and related processes but the impact
of cortical iron on task-relevant, cortical brain networks is unknown. We hypothesized that …