Changes in the microbial community structure are observed in individuals with intestinal
inflammatory disorders. These changes are often characterized by a depletion of obligate …

Nitrogen metabolism has attracted attention from a variety of viewpoints. The most familiar is
that of nutrition, and the importance of nitrogen assimilation for biosynthetic purposes is well …

Nitrate is a significant nitrogen source for plants and microorganisms. Recent molecular
genetic analyses of representative bacterial species have revealed structural and regulatory …

Synthesis of most anaerobic respiratory pathways is subject to dual regulation by anaerobiosis
and nitrate. Anaerobic induction is mediated by the FNR protein. Dual interacting two‐…

Two sensor proteins, NarX and NarQ, mediate nitrate regulation of anaerobic respiratory
gene expression. Either of these sensors is sufficient to signal the presence of nitrate to the …

The background to this manual was a course in advanced bacterial genetics taught by the
authors at the Cold Spring Harbor Laboratory from 1991 to 1995. It deals with genetic mapping…

Escherichia coli strain MG1655 was chosen for sequencing because the few mutations it
carries (ilvG rfb-50 rph-1) were considered innocuous. However, it has a number of growth …

Escherichia coli possesses a soluble flavohemoglobin, with an unknown function, encoded
by the hmp gene. A monolysogen containing an hmp-lacZ operon fusion was constructed to …

The study of bacterial pathogens with genetic methods is a new and explosive field set to
dominate microbiology in the next decade. Five years' progressive refinement in the celebrated …

Periplasmic nitrate reductase (NapABC enzyme) has been characterized from a variety of
proteobacteria, especially Paracoccus pantotrophus. Whole-genome sequencing of …