The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+ dendritic cells

K Crozat, R Guiton, V Contreras, V Feuillet… - Journal of Experimental …, 2010 - rupress.org
Human BDCA3 + dendritic cells (DCs) were suggested to be homologous to mouse CD8α +
DCs. We demonstrate that human BDCA3 + DCs are more efficient than their BDCA1 + …

[HTML][HTML] Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates

P Maisonnasse, J Guedj, V Contreras, S Behillil… - Nature, 2020 - nature.com
Coronavirus disease 2019 (COVID-19) has rapidly become a global pandemic and no antiviral
drug or vaccine is yet available for the treatment of this disease 1 , 2 – 3 . Several clinical …

Bluetongue virus: virology, pathogenesis and immunity

I Schwartz-Cornil, P Mertens, V Contreras… - Veterinary …, 2008 - hal.science
Bluetongue (BT) virus, an orbivirus of the Reoviridae family encompassing 24 known
serotypes, is transmitted to ruminants via certain species of biting midges (Culicoides spp.) and …

[PDF][PDF] Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

…, TG Caniels, J van Schooten, N Kahlaoui, V Contreras… - Cell, 2021 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is continuing
to disrupt personal lives, global healthcare systems, and economies. Hence, there is an …

SARS-CoV-2 infection in nonhuman primates alters the composition and functional activity of the gut microbiota

H Sokol, V Contreras, P Maisonnasse, A Desmons… - Gut …, 2021 - Taylor & Francis
The current pandemic of coronavirus disease (COVID) 2019 constitutes a global public
health issue. Regarding the emerging importance of the gut-lung axis in viral respiratory …

Existence of CD8α-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species

V Contreras, C Urien, R Guiton… - The Journal of …, 2010 - journals.aai.org
The mouse lymphoid organ-resident CD8α+ dendritic cell (DC) subset is specialized in Ag
presentation to CD8+ T cells. Recent evidence shows that mouse nonlymphoid tissue CD103…

[HTML][HTML] Antiviral efficacy of favipiravir against Zika and SARS-CoV-2 viruses in non-human primates

R Marlin, D Desjardins, V Contreras, G Lingas… - Nature …, 2022 - nature.com
The COVID-19 pandemic has exemplified that rigorous evaluation in large animal models is
key for translation from promising in vitro results to successful clinical implementation. …

Bluetongue virus targets conventional dendritic cells in skin lymph

B Hemati, V Contreras, C Urien, M Bonneau… - Journal of …, 2009 - Am Soc Microbiol
Bluetongue virus (BTV) is the etiological agent of bluetongue, a hemorrhagic disease of
ruminants (particularly sheep), which causes important economic losses around the world. BTV …

[HTML][HTML] SARS-CoV-2 viral dynamics in non-human primates

…, F Donati, M Albert, S Behillil, V Contreras… - PLoS computational …, 2021 - journals.plos.org
Non-human primates infected with SARS-CoV-2 exhibit mild clinical signs. Here we used a
mathematical model to characterize in detail the viral dynamics in 31 cynomolgus macaques …

[HTML][HTML] COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

…, CE Mire, MJ van Breemen, V Contreras… - Nature …, 2021 - nature.com
Effective treatments against Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2)
are urgently needed. Monoclonal antibodies have shown promising results in patients. …