[HTML][HTML] Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature
…, SJ Burgess, SFS Guerra, VT Bortoluzzi… - Research Integrity and …, 2020 - Springer
Background Preprint usage is growing rapidly in the life sciences; however, questions
remain on the relative quality of preprints when compared to published articles. An objective …
remain on the relative quality of preprints when compared to published articles. An objective …
Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature
OB Amaral, VT Bortoluzzi, SFS Guerra, SJ Burgess… - 2020 - philpapers.org
BackgroundPreprint usage is growing rapidly in the life sciences; however, questions
remain on the relative quality of preprints when compared to published articles. An objective …
remain on the relative quality of preprints when compared to published articles. An objective …
Oxidative stress in phenylketonuria—evidence from human studies and animal models, and possible implications for redox signaling
VT Bortoluzzi, CS Dutra Filho… - Metabolic Brain Disease, 2021 - Springer
Phenylketonuria (PKU) is one of the commonest inborn error of amino acid metabolism. Before
mass neonatal screening was possible, and the success of introducing diet therapy right …
mass neonatal screening was possible, and the success of introducing diet therapy right …
Disturbance of mitochondrial functions caused by N-acetylglutamate and N-acetylmethionine in brain of adolescent rats: Potential relevance in aminoacylase 1 …
VT Bortoluzzi, RT Ribeiro, ÂB Zemniaçak… - Neurochemistry …, 2023 - Elsevier
Aminoacylase 1 (ACY1) deficiency is a rare genetic disorder that affects the breakdown of
short-chain aliphatic N-acetylated amino acids, leading to the accumulation of these amino …
short-chain aliphatic N-acetylated amino acids, leading to the accumulation of these amino …
N-Acetylglutamate and N-acetylmethionine compromise mitochondrial bioenergetics homeostasis and glutamate oxidation in brain of developing rats: Potential …
VT Bortoluzzi, RT Ribeiro, CV Pinheiro… - Biochemical and …, 2023 - Elsevier
Aminoacylase 1 (ACY1) deficiency is an inherited metabolic disorder biochemically characterized
by high urinary concentrations of aliphatic N-acetylated amino acids and associated …
by high urinary concentrations of aliphatic N-acetylated amino acids and associated …
Co-administration of creatine plus pyruvate prevents the effects of phenylalanine administration to female rats during pregnancy and lactation on enzymes activity of …
VT Bortoluzzi, ID de Franceschi, E Rieger… - Neurochemical …, 2014 - Springer
Phenylketonuria (PKU) is the most frequent inborn error of metabolism. It is caused by deficiency
in the activity of phenylalanine hydroxylase, leading to accumulation of phenylalanine …
in the activity of phenylalanine hydroxylase, leading to accumulation of phenylalanine …
Creatine plus pyruvate supplementation prevents oxidative stress and phosphotransfer network disturbances in the brain of rats subjected to chemically-induced …
VT Bortoluzzi, L Brust, T Preissler… - Metabolic Brain …, 2019 - Springer
Phenylketonuria (PKU) is the most common inborn error of amino acid metabolism. Usually
diagnosed within the first month of birth, it is essential that the patient strictly follow the …
diagnosed within the first month of birth, it is essential that the patient strictly follow the …
Phenylalanine induces oxidative stress and decreases the viability of rat astrocytes: possible relevance for the pathophysiology of neurodegeneration in …
…, EK Fernandes, E Rieger, VT Bortoluzzi… - Metabolic brain …, 2016 - Springer
The aim of this study was to investigate the effects of phenylalanine on oxidative stress and
some metabolic parameters in astrocyte cultures from newborn Wistar rats. Astrocytes were …
some metabolic parameters in astrocyte cultures from newborn Wistar rats. Astrocytes were …
Prostaglandin E2 potentiates methylmalonate‐induced seizures
…, AT Gomes, LM Rambo, LM Bueno, VT Bortoluzzi… - …, 2012 - Wiley Online Library
Purpose: Methylmalonic acidemias are inherited metabolic disorders characterized by
methylmalonate (MMA) accumulation and neurologic dysfunction, including seizures. It is known …
methylmalonate (MMA) accumulation and neurologic dysfunction, including seizures. It is known …
Ibuprofen during gestation prevents some changes in physical and reflex development in offspring in a model of hyperleucinemia and maternal inflammation
…, VT Bortoluzzi, E Rieger, T Preissler… - International Journal …, 2020 - Wiley Online Library
Maple Syrup Urine Disease (MSUD) is caused by a severe deficiency in the branched‐chain
ketoacid dehydrogenase complex activity. Patients MSUD accumulate the branched‐chain …
ketoacid dehydrogenase complex activity. Patients MSUD accumulate the branched‐chain …