[PDF][PDF] Interface contractility between differently fated cells drives cell elimination and cyst formation

C Bielmeier, S Alt, V Weichselberger, M La Fortezza… - Current Biology, 2016 - cell.com
Although cellular tumor-suppression mechanisms are widely studied, little is known about
mechanisms that act at the level of tissues to suppress the occurrence of aberrant cells in …

Response of Drosophila epithelial cell and tissue shape to external forces in vivo

R Balaji, V Weichselberger, AK Classen - Development, 2019 - journals.biologists.com
How actomyosin generates forces at epithelial adherens junctions has been extensively
studied. However, less is known about how a balance between internal and external forces …

[HTML][HTML] Mutual repression between JNK/AP-1 and JAK/STAT stratifies senescent and proliferative cell behaviors during tissue regeneration

…, AA Peyrotón, L Nogay, V Weichselberger… - PLoS …, 2023 - journals.plos.org
Epithelial repair relies on the activation of stress signaling pathways to coordinate tissue
repair. Their deregulation is implicated in chronic wound and cancer pathologies. Using TNF-α/…

[HTML][HTML] Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis

V Weichselberger, P Dondl, AK Classen - Nature communications, 2022 - nature.com
Cooperative morphogenesis of cell lineages underlies the development of functional units
and organs. To study mechanisms driving the coordination of lineages, we investigated soma-…

Mutual repression between JNK/AP-1 and JAK/STAT stratifies cell behaviors during tissue regeneration

J Jaiswal, R Engesser, AA Peyroton, V Weichselberger… - Biorxiv, 2022 - biorxiv.org
Epithelial repair relies on the activation of stress signaling pathways to coordinate cellular
repair behaviors. Their deregulation is implicated in chronic wound and cancer pathologies. …

A cell surface code mediates tissue-intrinsic defense against aberrant cells in epithelia

…, A Frey, K Holstein, D Prasad, V Weichselberger… - bioRxiv, 2023 - biorxiv.org
Tissue-intrinsic error-correction mechanisms allow epithelial cells to detect aberrant neighboring
cells and cause their removal from the tissue. The molecular mechanisms which grant …

Regulation of tensile stress in response to external forces coordinates epithelial cell shape transitions with organ growth and elongation

R Balaji, V Weichselberger, AK Classen - bioRxiv, 2018 - biorxiv.org
The role of actomyosin contractility at epithelial adherens junctions has been extensively
studied. However, little is known about how external forces are integrated to establish epithelial …

[PDF][PDF] A mismatch in the expression of cell surface molecules induces tissue-intrinsic defense against aberrant cells

…, A Frey, K Holstein, D Prasad, V Weichselberger… - Current Biology, 2024 - cell.com
Tissue-intrinsic error correction enables epithelial cells to detect abnormal neighboring cells
and facilitate their removal from the tissue. One of these pathways, "interface surveillance," …

[PDF][PDF] Transient opening of tricellular vertices controls paracellular transport through the follicle epithelium during Drosophila oogenesis

J Isasti-Sanchez, F Münz-Zeise, M Lancino… - Developmental Cell, 2021 - cell.com
Paracellular permeability is regulated to allow solute transport or cell migration across epithelial
or endothelial barriers. However, how cell-cell junction dynamics controls paracellular …

[HTML][HTML] Posterior segment ophthalmic drug delivery: Role of muco-adhesion with a special focus on chitosan

AM Burhan, B Klahan, W Cummins, V Andrés-Guerrero… - Pharmaceutics, 2021 - mdpi.com
Posterior segment eye diseases (PSEDs) including age macular degeneration (AMD) and
diabetic retinopathy (DR) are amongst the major causes of irreversible blindness worldwide. …