Induction of broad-based immunity and protective efficacy by self-amplifying mRNA vaccines encoding influenza virus hemagglutinin
…, S Buccato, C Giovani, R Kratzer, V Zurli… - Journal of …, 2016 - Am Soc Microbiol
Seasonal influenza is a vaccine-preventable disease that remains a major health problem
worldwide, especially in immunocompromised populations. The impact of influenza disease is …
worldwide, especially in immunocompromised populations. The impact of influenza disease is …
[HTML][HTML] Signals controlling lytic granule polarization at the cytotoxic immune synapse
A Kabanova, V Zurli, CT Baldari - Frontiers in immunology, 2018 - frontiersin.org
Cytotoxic immunity relies on specialized effector T cells, the cytotoxic T cells, which are
endowed with specialized cytolytic machinery that permits them to induce death of their targets. …
endowed with specialized cytolytic machinery that permits them to induce death of their targets. …
Phosphoproteomics of CD2 signaling reveals AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells
V Zurli, T Montecchi, R Heilig, I Poschke, M Volkmar… - Science …, 2020 - science.org
Understanding the costimulatory signaling that enhances the activity of cytotoxic T cells (CTLs)
could identify potential targets for immunotherapy. Here, we report that CD2 costimulation …
could identify potential targets for immunotherapy. Here, we report that CD2 costimulation …
Ectopic ILT3 controls BCR-dependent activation of Akt in B-cell chronic lymphocytic leukemia
V Zurli, G Wimmer, F Cattaneo, V Candi… - Blood, The Journal …, 2017 - ashpublications.org
The high proportion of long-term nonprogressors among chronic lymphocytic leukemia (CLL)
patients suggests the existence of a regulatory network that restrains the proliferation of …
patients suggests the existence of a regulatory network that restrains the proliferation of …
Positive contribution of adjuvanted influenza vaccines to the resolution of bacterial superinfections
V Zurli, M Gallotta, M Taccone, E Chiarot… - The Journal of …, 2016 - academic.oup.com
Background. Most preclinical studies assess vaccine effectiveness in single-pathogen
infection models. This is unrealistic given that humans are continuously exposed to different …
infection models. This is unrealistic given that humans are continuously exposed to different …
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eμ-TCL1 mice through the …
F Vanni, L Lopresti, V Zurli, A Kabanova… - Pharmacological …, 2021 - Elsevier
Survival and expansion of malignant B cells in chronic lymphocytic leukemia (CLL) are highly
dependent both on intrinsic defects in the apoptotic machinery and on the interactions with …
dependent both on intrinsic defects in the apoptotic machinery and on the interactions with …
[HTML][HTML] The Neisseria meningitidis ADP-Ribosyltransferase NarE Enters Human Epithelial Cells and Disrupts Epithelial Monolayer Integrity
Many pathogenic bacteria utilize ADP-ribosylating toxins to modify and impair essential
functions of eukaryotic cells. It has been previously reported that Neisseria meningitidis …
functions of eukaryotic cells. It has been previously reported that Neisseria meningitidis …
Phosphoproteomic analysis of CD2 signaling reveals an AMPK-dependent targeted granule secretion in human cytotoxic T cells
V Zurli, T Montecchi, H Raphael, P Isabel… - SCIENCE …, 2020 - usiena-air.unisi.it
Understanding the costimulatory signaling that enhances the activity of cytotoxic T cells (CTLs)
could identify potential targets for immunotherapy. Here, we report that CD2 costimulation …
could identify potential targets for immunotherapy. Here, we report that CD2 costimulation …
Novel strategies to improve anti-influenza vaccines. Positive contribution of adjuvanted immunization strategies during aging and in the resolution of viral-bacterial co …
V Zurli - 2016 - research.unipd.it
Despite the extensive use of anti-influenza vaccines during the last decades, influenza and
its complications are still a major cause of morbidity and mortality worldwide. Older adults (>…
its complications are still a major cause of morbidity and mortality worldwide. Older adults (>…
[CITATION][C] Unravelling the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the pyrrolonaphthoxazepines (PNOXs)
…, T Khan, DM Zisterer, C Francesca, V Zurli… - Abstract book 5th …, 2019 - usiena-air.unisi.it
… Vanni, F., Lopresti, L., Khan, T., Zisterer, DM, Francesca, C., Zurli, V., et al. (2019). Unravelling
the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the …
the response of chronic lymphocytic leukemia to a novel class of anticancer agents, the …