Genomic epidemiology reveals multiple introductions of Zika virus into the United States

…, PN Lichtenberger, MJ Ricciardi, VK Bailey… - Nature, 2017 - nature.com
Zika virus (ZIKV) is causing an unprecedented epidemic linked to severe congenital abnormalities
1 , 2 . In July 2016, mosquito-borne ZIKV transmission was reported in the continental …

Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques

…, MW Burke, DM Magnani, VK Bailey… - Science translational …, 2018 - science.org
The Zika virus (ZIKV) epidemic is associated with fetal brain lesions and other serious birth
defects classified as congenital ZIKV syndrome. Postnatal ZIKV infection in infants and …

Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques

…, N Beutler, MJ Ricciardi, VK Bailey… - Science translational …, 2017 - science.org
Therapies to prevent maternal Zika virus (ZIKV) infection and its subsequent fetal
developmental complications are urgently required. We isolated three potent ZIKV-neutralizing …

[HTML][HTML] Fetal demise and failed antibody therapy during Zika virus infection of pregnant macaques

…, ND Grubaugh, N Beutler, VK Bailey… - Nature …, 2018 - nature.com
Zika virus (ZIKV) infection of pregnant women is associated with pathologic complications of
fetal development. Here, we infect pregnant rhesus macaques (Macaca mulatta) with a …

[HTML][HTML] Ontogeny of the B-and T-cell response in a primary Zika virus infection of a dengue-naive individual during the 2016 outbreak in Miami, FL

…, M Sharkey, CGT Silveira, VK Bailey… - PLoS neglected …, 2017 - journals.plos.org
Zika virus (ZIKV) is a mosquito-borne flavivirus of significant public health concern. In the
summer of 2016, ZIKV was first detected in the contiguous United States. Here we present one …

Potent plasmablast-derived antibodies elicited by the national institutes of health dengue vaccine

…, N Pedreño-Lopez, VK Bailey… - Journal of …, 2017 - Am Soc Microbiol
Exposure to dengue virus (DENV) is thought to elicit lifelong immunity, mediated by DENV-neutralizing
antibodies (nAbs). However, Abs generated by primary infections confer serotype-…

[HTML][HTML] Dengue virus evades AAV-mediated neutralizing antibody prophylaxis in rhesus monkeys

DM Magnani, MJ Ricciardi, VK Bailey, MJ Gutman… - Molecular therapy, 2017 - cell.com
Development of vaccines against mosquito-borne Flaviviruses is complicated by the occurrence
of antibody-dependent enhancement (ADE), which can increase disease severity. Long-…

[HTML][HTML] A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus

…, N Pedreño-Lopez, MJ Gutman, VK Bailey… - PLoS neglected …, 2017 - journals.plos.org
The isolation of neutralizing monoclonal antibodies (nmAbs) against the Zika virus (ZIKV)
might lead to novel preventative strategies for infections in at-risk individuals, primarily …

Rectal acquisition of simian immunodeficiency virus (SIV) SIVmac239 infection despite vaccine-induced immune responses against the entire SIV proteome

…, L Gonzalez-Nieto, MJ Ricciardi, VK Bailey… - Journal of …, 2020 - Am Soc Microbiol
Given the complex biology of human immunodeficiency virus (HIV) and its remarkable capacity
to evade host immune responses, HIV vaccine efficacy may benefit from the induction of …

Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication

…, VK Bailey, JD Altman, DR Burton, K Ejima… - Journal of …, 2018 - Am Soc Microbiol
Certain major histocompatibility complex class I (MHC-I) alleles are associated with spontaneous
control of viral replication in human immunodeficiency virus (HIV)-infected people and …