[HTML][HTML] Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway

VC Anipindi, P Bagri, K Roth, SE Dizzell… - PLoS …, 2016 - journals.plos.org
Clinical and experimental studies have shown that estradiol (E2) confers protection against
HIV and other sexually transmitted infections. Here, we investigated the underlying …

Novel role for interleukin-17 in enhancing type 1 helper T cell immunity in the female genital tract following mucosal herpes simplex virus 2 vaccination

P Bagri, VC Anipindi, PV Nguyen, D Vitali… - Journal of …, 2017 - Am Soc Microbiol
It is well established that interferon gamma (IFN-γ) production by CD4 + T cells is critical for
antiviral immunity against herpes simplex virus 2 (HSV-2) genital infection. However, the role …

[HTML][HTML] Microbial regulation of enteric eosinophils and its impact on tissue remodeling and Th2 immunity

R Jiménez-Saiz, VC Anipindi, H Galipeau… - Frontiers in …, 2020 - frontiersin.org
Eosinophils have emerged as multifaceted cells that contribute to tissue homeostasis.
However, the impact of the microbiota on their frequency and function at mucosal sites remains …

Specific binding to differentially expressed human carcinoembryonic antigen-related cell adhesion molecules determines the outcome of Neisseria gonorrhoeae …

EA Islam, VC Anipindi, I Francis… - Infection and …, 2018 - Am Soc Microbiol
The gonococcal Opa proteins are an antigenically variable family of surface adhesins that
bind human carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), …

[HTML][HTML] High physiological concentrations of progesterone reverse estradiol-mediated changes in differentiation and functions of bone marrow derived dendritic cells

F Xiu, VC Anipindi, PV Nguyen, J Boudreau, H Liang… - PLoS …, 2016 - journals.plos.org
Female sex steroids, estradiol (E2) and progesterone (P4), play a key role in regulating
immune responses in women, including dendritic cell (DC) development, and functions. …

[HTML][HTML] IL-17 production by γδ+ T cells is critical for inducing Th17 responses in the female genital tract and regulated by estradiol and microbiota

VC Anipindi, P Bagri, SE Dizzell, R Jiménez-Saiz… - …, 2019 - journals.aai.org
IL-17 can be produced by adaptive immune cells such as T h 17 cells and by immune cells
that produce IL-17 without prior priming. This latter category, which we will refer to as “innate,” …

[HTML][HTML] The role of IL-17 during infections in the female reproductive tract

P Bagri, VC Anipindi, C Kaushic - Frontiers in Immunology, 2022 - frontiersin.org
Interleukin-17 (IL-17A) is a cytokine involved in a complex array of both protective and
detrimental processes. Although early biological studies focused on the pro-inflammatory function …

[PDF][PDF] Specific binding to differentially-expressed human CEACAMs determines the outcome of Neisseria gonorrhoeae infections along the female reproductive tract

EA Islam, VC Anipindi, I Francis… - Infect …, 2018 - researchgate.net
… Epshita Islam: Designed and performed experiments, analyzed data and wrote the paper
662 Varun C. Anipindi and Charu Kaushic: Contributed data for Figures 1 and 2 663 Ian Francis…

Influence of bacterial components on the developmental programming of enteric neurons

…, F Markovic, R Borojevic, VC Anipindi… - Physiological …, 2020 - Wiley Online Library
Background Intestinal bacteria have been increasingly shown to be involved in early
postnatal development. Previous work has shown that intestinal bacteria are necessary for the …

Correction: Estradiol Enhances CD4+ T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce Th17 Responses via an IL-1-Dependent Pathway

VC Anipindi, P Bagri, K Roth, SE Dizzell… - Plos …, 2016 - journals.plos.org
Anipindi, Puja Bagri, Kristy Roth, Sara E. Dizzell, Philip V. Nguyen, Christopher R. …
Anipindi VC, Bagri P, Roth K, Dizzell SE, Nguyen PV, Shaler CR, et al. (2016) Estradiol …