User profiles for Venkatesh N. Murthy

Venkatesh N. Murthy

Professor of MCB & Director of Center for Brain Science, Harvard University
Verified email at fas.harvard.edu
Cited by 17784

DeepLabCut: markerless pose estimation of user-defined body parts with deep learning

…, P Mamidanna, KM Cury, T Abe, VN Murthy… - Nature …, 2018 - nature.com
Quantifying behavior is crucial for many applications in neuroscience. Videography provides
easy methods for the observation and recording of animal behavior in diverse settings, yet …

Coherent 25-to 35-Hz oscillations in the sensorimotor cortex of awake behaving monkeys.

VN Murthy, EE Fetz - … of the National Academy of Sciences, 1992 - National Acad Sciences
Synchronous 25- to 35-Hz oscillations were observed in local field potentials and unit activity
in sensorimotor cortex of awake rhesus monkeys. The oscillatory episodes occurred often …

All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

…, M Melkonian, GKS Wong, DJ Harrison, VN Murthy… - Nature …, 2014 - nature.com
All-optical electrophysiology—spatially resolved simultaneous optical perturbation and
measurement of membrane voltage—would open new vistas in neuroscience research. We …

[PDF][PDF] Inactivity produces increases in neurotransmitter release and synapse size

VN Murthy, T Schikorski, CF Stevens, Y Zhu - Neuron, 2001 - cell.com
When hippocampal synapses in culture are pharmacologically silenced for several days,
synaptic strength increases. The structural correlate of this change in strength is an increase in …

[PDF][PDF] Heterogeneous release properties of visualized individual hippocampal synapses

VN Murthy, TJ Sejnowski, CF Stevens - Neuron, 1997 - cell.com
We have used endocytotic uptake of the styryl dye FM1–43 at synaptic terminals (Betz and
Bewick 1992) to study properties of individual synapses formed by axons of single …

Multiple forms of synaptic plasticity triggered by selective suppression of activity in individual neurons

J Burrone, M O'Byrne, VN Murthy - Nature, 2002 - nature.com
The rules by which neuronal activity causes long-term modification of synapses in the central
nervous system are not fully understood. Whereas competitive or correlation-based rules …

Rapid turnover of actin in dendritic spines and its regulation by activity

EN Star, DJ Kwiatkowski, VN Murthy - Nature neuroscience, 2002 - nature.com
Dendritic spines are motile structures that contain high concentrations of filamentous actin.
Using hippocampal neurons expressing fluorescent actin and the method of fluorescence …

Oscillatory activity in sensorimotor cortex of awake monkeys: synchronization of local field potentials and relation to behavior

VN Murthy, EE Fetz - Journal of neurophysiology, 1996 - journals.physiology.org
1. Oscillations of 20-40 Hz were observed in local field potentials (LFPs) and unit activity in
sensorimotor cortices of three awake monkeys while the monkeys performed trained wrist …

[HTML][HTML] Multi-animal pose estimation, identification and tracking with DeepLabCut

…, V Di Santo, D Soberanes, G Feng, VN Murthy… - Nature …, 2022 - nature.com
Estimating the pose of multiple animals is a challenging computer vision problem: frequent
interactions cause occlusions and complicate the association of detected keypoints to the …

Gradients of substrate-bound laminin orient axonal specification of neurons

…, X Jiang, Z Li, VN Murthy… - Proceedings of the …, 2002 - National Acad Sciences
Little is known about the influence of substrate-bound gradients on neuronal development,
since it has been difficult to fabricate gradients over the distances typically required for …