[HTML][HTML] Microfluidics for biotechnology: bridging gaps to foster microfluidic applications
V Ortseifen, M Viefhues, L Wobbe… - … in Bioengineering and …, 2020 - frontiersin.org
Microfluidics and novel lab-on-a-chip applications have the potential to boost biotechnological
research in ways that are not possible using traditional methods. Although microfluidic …
research in ways that are not possible using traditional methods. Although microfluidic …
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms
We need to effectively combine the knowledge from surging literature with complex datasets
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
Comparative proteome analysis of Actinoplanes sp. SE50/110 grown with maltose or glucose shows minor differences for acarbose biosynthesis proteins but major …
Actinoplanes sp. SE50/110 is known for the production of the α-glucosidase inhibitor and
anti-diabetic drug acarbose. Acarbose (acarviosyl-maltose) is produced as the major product …
anti-diabetic drug acarbose. Acarbose (acarviosyl-maltose) is produced as the major product …
[HTML][HTML] Analysis of Gum proteins involved in xanthan biosynthesis throughout multiple cell fractions in a “single-tube”
Xanthomonas is a phytopathogenic bacterium and of industrial interest due to its capability
to produce xanthan, used as a thickener and emulsifier in the food and non-food industry. …
to produce xanthan, used as a thickener and emulsifier in the food and non-food industry. …
An integrated metagenome and-proteome analysis of the microbial community residing in a biogas production plant
To study the metaproteome of a biogas-producing microbial community, fermentation samples
were taken from an agricultural biogas plant for microbial cell and protein extraction and …
were taken from an agricultural biogas plant for microbial cell and protein extraction and …
Flavin‐Dependent Halogenases from Xanthomonas campestris pv. campestris B100 Prefer Bromination over Chlorination
…, M Frese, T Patschkowski, V Ortseifen… - Advanced Synthesis …, 2019 - Wiley Online Library
Flavin‐dependent halogenases selectively introduce halogen substituents into (hetero‐)aromatic
substrates and require only molecular oxygen and halide salts for this regioselective …
substrates and require only molecular oxygen and halide salts for this regioselective …
[HTML][HTML] Two flagellar mutants of Xanthomonas campestris are characterized by enhanced xanthan production and higher xanthan viscosity
Xanthomonas campestris strains are used world-wide for the production of the industrially
important exopolysaccharide xanthan. The high industrial relevance of xanthan can be …
important exopolysaccharide xanthan. The high industrial relevance of xanthan can be …
Genetic engineering in Actinoplanes sp. SE50/110− development of an intergeneric conjugation system for the introduction of actinophage-based integrative vectors
The α-glucosidase inhibitor acarbose is used for treatment of diabetes mellitus type II, and is
manufactured industrially with overproducing derivatives of Actinoplanes sp. SE50/110, …
manufactured industrially with overproducing derivatives of Actinoplanes sp. SE50/110, …
Comprehensive proteome analysis of Actinoplanes sp. SE50/110 highlighting the location of proteins encoded by the acarbose and the pyochelin biosynthesis gene …
Acarbose is an α-glucosidase inhibitor produced by Actinoplanes sp. SE50/110 that is
medically important due to its application in the treatment of type2 diabetes. In this work, a …
medically important due to its application in the treatment of type2 diabetes. In this work, a …
[HTML][HTML] The MalR type regulator AcrC is a transcriptional repressor of acarbose biosynthetic genes in Actinoplanes sp. SE50/110
T Wolf, J Droste, T Gren, V Ortseifen… - BMC genomics, 2017 - Springer
Background Acarbose is used in the treatment of diabetes mellitus type II and is produced
by Actinoplanes sp. SE50/110. Although the biosynthesis of acarbose has been intensively …
by Actinoplanes sp. SE50/110. Although the biosynthesis of acarbose has been intensively …