User profiles for Verena Börger

Verena Börger

University Hospital Essen
Verified email at uk-essen.de
Cited by 2908

Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper

T Lener, M Gimona, L Aigner, V Börger… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …

[HTML][HTML] Mesenchymal stem/stromal cell-derived extracellular vesicles and their potential as novel immunomodulatory therapeutic agents

V Börger, M Bremer, R Ferrer-Tur, L Gockeln… - International journal of …, 2017 - mdpi.com
Verena Börger and Michel Bremer designed the concept and organized the writing of the
manuscript… The final version of the manuscript was edited by Verena Börger and Bernd Giebel. …

Precipitation with polyethylene glycol followed by washing and pelleting by ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small …

…, K De Miroschedji, TR Doeppner, V Börger… - Journal of …, 2018 - Taylor & Francis
Extracellular vesicles (EVs) provide a complex means of intercellular signalling between cells
at local and distant sites, both within and between different organs. According to their cell-…

[HTML][HTML] Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain …

…, T Hussner, Y Qi, T Tertel, V Börger… - Basic research in …, 2021 - Springer
Obtained from the right cell-type, mesenchymal stromal cell (MSC)-derived small extracellular
vesicles (sEVs) promote stroke recovery. Within this process, microvascular remodeling …

Scaled preparation of extracellular vesicles from conditioned media

S Staubach, FN Bauer, T Tertel, V Börger… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) especially of mesenchymal stem/stomal cells (MSCs) are increasingly
considered as biotherapeutic agents for a variety of different diseases. For translating …

Mesenchymal Stromal Cell–Derived Small Extracellular Vesicles Induce Ischemic Neuroprotection by Modulating Leukocytes and Specifically Neutrophils

C Wang, V Börger, M Sardari, F Murke, J Skuljec, R Pul… - Stroke, 2020 - Am Heart Assoc
Background and Purpose— Small extracellular vesicles (sEVs) obtained from mesenchymal
stromal cells (MSCs) were shown to induce neurological recovery after focal cerebral …

[HTML][HTML] Clinical potential of mesenchymal stem/stromal cell-derived extracellular vesicles

B Giebel, L Kordelas, V Börger - Stem cell investigation, 2017 - ncbi.nlm.nih.gov
Within the last two decades mesenchymal stem/stromal cells (MSCs) emerged after hematopoietic
stem cells as the second most investigated and applied somatic stem cell entity so far. …

International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells …

V Börger, DJ Weiss, JD Anderson, FE Borràs… - Cytotherapy, 2020 - Elsevier
STATEMENT: The International Society for Cellular and Gene Therapies (ISCT) and the
International Society for Extracellular Vesicles (ISEV) recognize the potential of extracellular …

[HTML][HTML] Mesenchymal stromal cell-derived extracellular vesicles reduce neuroinflammation, promote neural cell proliferation and improve oligodendrocyte maturation …

N Kaminski, C Köster, Y Mouloud, V Börger… - Frontiers in Cellular …, 2020 - frontiersin.org
Background: Neonatal encephalopathy caused by hypoxia-ischemia (HI) is a major cause of
childhood mortality and disability. Stem cell-based regenerative therapies seem promising …

Scaled Isolation of Mesenchymal Stem/Stromal Cell‐Derived Extracellular Vesicles

V Börger, S Staubach, R Dittrich… - Current protocols in …, 2020 - Wiley Online Library
Mesenchymal stem/stromal cells (MSCs) provide therapeutic effects in many diseases.
Contrary to initial hypotheses, they act in a paracrine rather than a cellular manner. To this end, …