Many viral infections cause acute and chronic neurologic diseases which can lead to degeneration
of cortical functions. While neurotropic viruses that gain access to the central nervous …

Background DNA methylation is an important epigenetic mark that can potentially link early
life exposures to adverse health outcomes later in life. Host factors like sex and age strongly …

Mucosal infections pose a significant global health burden. Antigen-specific tissue-resident
T cells are critical to maintaining barrier immunity. Previous studies in the context of systemic …

Chronic viral infections are known to lead to T cell exhaustion or dysfunction. However, it
remains unclear if antigen exposure episodes from periodic viral reactivation, such as herpes …

Background Emerging RNA viruses that target the central nervous system (CNS) lead to
cognitive sequelae in survivors. Studies in humans and mice infected with West Nile virus (WNV)…

Background: The childhood salivary microbiome, which plays an important role in healthy
development, may be influenced by breast milk consumption. The composition of the milk …

The mechanisms underlying rapid elimination of herpes simplex virus-2 (HSV-2) in the
human genital tract despite low CD8 + and CD4 + tissue-resident T cell (Trm cell) density are …

Objectives To address molecular mechanisms underlying obesity development, we
examined patterns of critical metabolism-related hormones, adiponectin and leptin (adipokines), …

Bisphenol A (BPA) is a high volume production chemical that has been detected in 93% of
the United States population. It is thought to have endocrine disrupting activity but human …

Innate immune responses to emerging RNA viruses are increasingly recognized as having
significant contributions to neurologic sequelae, especially memory disorders. Using a …