User profiles for Veronika I. Zarnitsyna
Veronika ZarnitsynaEmory University Verified email at emory.edu Cited by 4268 |
Mechanisms for flow-enhanced cell adhesion
Cell adhesion is mediated by specific receptor–ligand bonds. In several biological systems,
increasing flow has been observed to enhance cell adhesion despite the increasing …
increasing flow has been observed to enhance cell adhesion despite the increasing …
[PDF][PDF] Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells
Ending the COVID-19 pandemic will require long-lived immunity to SARS-CoV-2. Here, we
evaluate 254 COVID-19 patients longitudinally up to 8 months and find durable broad-based …
evaluate 254 COVID-19 patients longitudinally up to 8 months and find durable broad-based …
Insights from in situ analysis of TCR–pMHC recognition: response of an interaction network
Recognition of peptide presented by the major histocompatibility complex ( pMHC ) molecule
by the T‐cell receptor ( TCR ) determines T‐cell selection, development, differentiation, fate…
by the T‐cell receptor ( TCR ) determines T‐cell selection, development, differentiation, fate…
The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness
The T-cell receptor (TCR) interacts with peptide-major histocompatibility complexes (pMHC)
to discriminate pathogens from self-antigens and trigger adaptive immune responses. Direct …
to discriminate pathogens from self-antigens and trigger adaptive immune responses. Direct …
Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine
…, M Hu, AC Walls, VV Edara, VI Zarnitsyna… - Science translational …, 2022 - science.org
Despite the remarkable efficacy of COVID-19 vaccines, waning immunity and the emergence
of SARS-CoV-2 variants such as Omicron represents a global health challenge. Here, we …
of SARS-CoV-2 variants such as Omicron represents a global health challenge. Here, we …
[PDF][PDF] Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response
…, M Wehenkel, JC Crawford, VI Zarnitsyna… - Cell host & …, 2022 - cell.com
SARS-CoV-2 infection causes diverse outcomes ranging from asymptomatic infection to
respiratory distress and death. A major unresolved question is whether prior immunity to …
respiratory distress and death. A major unresolved question is whether prior immunity to …
Flow-enhanced adhesion regulated by a selectin interdomain hinge
…, AG Klopocki, P Mehta, W Chen, VI Zarnitsyna… - The Journal of cell …, 2006 - rupress.org
L-selectin requires a threshold shear to enable leukocytes to tether to and roll on vascular
surfaces. Transport mechanisms govern flow-enhanced tethering, whereas force governs flow-…
surfaces. Transport mechanisms govern flow-enhanced tethering, whereas force governs flow-…
Influenza immunization in the context of preexisting immunity
…, R Ahmed, VI Zarnitsyna - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
Although we develop influenza immunity from an early age, it is insufficient to prevent future
infection with antigenically novel strains. One proposed way to generate long-term protective …
infection with antigenically novel strains. One proposed way to generate long-term protective …
Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans
…, AJ Schmitz, VI Zarnitsyna… - Proceedings of the …, 2020 - National Acad Sciences
There is a need for improved influenza vaccines. In this study we compared the antibody
responses in humans after vaccination with an AS03-adjuvanted versus nonadjuvanted H5N1 …
responses in humans after vaccination with an AS03-adjuvanted versus nonadjuvanted H5N1 …
[HTML][HTML] Multi-epitope models explain how pre-existing antibodies affect the generation of broadly protective responses to influenza
The development of next-generation influenza vaccines that elicit strain-transcendent immunity
against both seasonal and pandemic viruses is a key public health goal. Targeting the …
against both seasonal and pandemic viruses is a key public health goal. Targeting the …