User profiles for Veronika I. Zarnitsyna

Veronika Zarnitsyna

Emory University
Verified email at emory.edu
Cited by 4268

Mechanisms for flow-enhanced cell adhesion

C Zhu, T Yago, J Lou, VI Zarnitsyna… - Annals of biomedical …, 2008 - Springer
Cell adhesion is mediated by specific receptor–ligand bonds. In several biological systems,
increasing flow has been observed to enhance cell adhesion despite the increasing …

[PDF][PDF] Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells

…, S Gunisetty, K Stephens, R Antia, VI Zarnitsyna… - Cell Reports …, 2021 - cell.com
Ending the COVID-19 pandemic will require long-lived immunity to SARS-CoV-2. Here, we
evaluate 254 COVID-19 patients longitudinally up to 8 months and find durable broad-based …

Insights from in situ analysis of TCR–pMHC recognition: response of an interaction network

C Zhu, N Jiang, J Huang, VI Zarnitsyna… - Immunological …, 2013 - Wiley Online Library
Recognition of peptide presented by the major histocompatibility complex ( pMHC ) molecule
by the T‐cell receptor ( TCR ) determines T‐cell selection, development, differentiation, fate…

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness

J Huang, VI Zarnitsyna, B Liu, LJ Edwards, N Jiang… - Nature, 2010 - nature.com
The T-cell receptor (TCR) interacts with peptide-major histocompatibility complexes (pMHC)
to discriminate pathogens from self-antigens and trigger adaptive immune responses. Direct …

Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine

…, M Hu, AC Walls, VV Edara, VI Zarnitsyna… - Science translational …, 2022 - science.org
Despite the remarkable efficacy of COVID-19 vaccines, waning immunity and the emergence
of SARS-CoV-2 variants such as Omicron represents a global health challenge. Here, we …

[PDF][PDF] Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response

…, M Wehenkel, JC Crawford, VI Zarnitsyna… - Cell host & …, 2022 - cell.com
SARS-CoV-2 infection causes diverse outcomes ranging from asymptomatic infection to
respiratory distress and death. A major unresolved question is whether prior immunity to …

Flow-enhanced adhesion regulated by a selectin interdomain hinge

…, AG Klopocki, P Mehta, W Chen, VI Zarnitsyna… - The Journal of cell …, 2006 - rupress.org
L-selectin requires a threshold shear to enable leukocytes to tether to and roll on vascular
surfaces. Transport mechanisms govern flow-enhanced tethering, whereas force governs flow-…

Influenza immunization in the context of preexisting immunity

…, R Ahmed, VI Zarnitsyna - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
Although we develop influenza immunity from an early age, it is insufficient to prevent future
infection with antigenically novel strains. One proposed way to generate long-term protective …

Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans

…, AJ Schmitz, VI Zarnitsyna… - Proceedings of the …, 2020 - National Acad Sciences
There is a need for improved influenza vaccines. In this study we compared the antibody
responses in humans after vaccination with an AS03-adjuvanted versus nonadjuvanted H5N1 …

[HTML][HTML] Multi-epitope models explain how pre-existing antibodies affect the generation of broadly protective responses to influenza

VI Zarnitsyna, J Lavine, A Ellebedy, R Ahmed… - PLoS …, 2016 - journals.plos.org
The development of next-generation influenza vaccines that elicit strain-transcendent immunity
against both seasonal and pandemic viruses is a key public health goal. Targeting the …