Cardiolipin is an ever-present component of the energy-conserving inner membranes of
bacteria and mitochondria. Its modulation of the structure and dynamism of the bilayer impacts …

The SecY/61 complex forms the protein-channel component of the ubiquitous protein secretion
and membrane protein insertion apparatus. The bacterial version SecYEG interacts with …

We employed electron cryo‐tomography to visualize cytosolic ribosomes on the surface of
mitochondria. Translation‐arrested ribosomes reveal the clustered organization of the TOM …

10.7554/eLife.07380.001 Proteins of the secretin family form large macromolecular complexes,
which assemble in the outer membrane of Gram-negative bacteria. Secretins are major …

Phages are viruses that infect bacteria and dominate every ecosystem on our planet. As well
as impacting microbial ecology, physiology and evolution, phages are exploited as tools in …

Bacteria and archaea possess a protein complex in the plasma membrane that governs
protein secretion and membrane protein insertion. Eukaryotes carry homologues in the …

The transcriptional termination of unstable non-coding RNAs (ncRNAs) is poorly understood
compared to coding transcripts. We recently identified ZC3H4-WDR82 ("restrictor") as …

Translational control is an essential process for the cell to adapt to varying physiological or
environmental conditions. To survive adverse conditions such as low nutrient levels, …

Unravelling the structural organization of membrane protein machines in their active state
and native lipid environment is a major challenge in modern cell biology research. Here we …

Pili are filamentous surface extensions that play roles in bacterial and archaeal cellular
processes such as adhesion, biofilm formation, motility, cell-cell communication, DNA uptake and …