Background & Aims: Studies have shown that gastric T cells are increased during Helicobacter
pylori infection. The purpose of this study was to characterize the human gastric T-cell …

Staphylococcus aureus (S. aureus) is a Gram positive bacterium that is carried by about one
third of the general population and is responsible for common and serious diseases. These …

Helicobacter pylori infection is associated with altered gastric epithelial cell turnover. To
evaluate the role of oxidative stress in cell death, gastric epithelial cells were exposed to various …

Helicobacter pylori infection is associated with gastritis, ulcers, and gastric cancer. The
infection becomes chronic as the host response is unable to clear it. Gastric epithelial cells (GEC) …

The gastrointestinal epithelium has cells with features that make them a powerful line of
defense in innate mucosal immunity. Features that allow gastrointestinal epithelial cells to …

Infection by Helicobacter pylori leads to injury of the gastric epithelium and a cellular infiltrate
that includes CD4+ T cells. H. pylori binds to class II MHC molecules on gastric epithelial …

Background & Aims: A prominent role for inhibitory molecules PD-L1 and PD-L2 in
peripheral tolerance has been proposed. However, the phenotype and function of PD-L–expressing …

Helicobacter pylori infection is associated with gastric epithelial damage, including apoptosis,
ulceration, and cancer. Although bacterial factors and the host response are believed to …

Helicobacter pylori (H. pylori) is perhaps the most ubiquitous and successful human
pathogen, since it colonizes the stomach of more than half of humankind. Infection with this …

The human gastrointestinal mucosa is exposed to a diverse normal microflora and dietary
Ags and is a common site of entry for pathogens. The mucosal immune system must respond …