We assembled an ancestrally diverse collection of genome-wide association studies (GWAS)
of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non…

Meta-analyses of genome-wide association studies (GWAS) have identified more than 240
loci that are associated with type 2 diabetes (T2D) 1 , 2 ; however, most of these loci have …

Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse
pathophysiological processes. To characterise the genetic contribution to these processes across …

We assembled an ancestrally diverse collection of genome-wide association studies of type
2 diabetes (T2D) in 180,834 cases and 1,159,055 controls (48.9% non-European descent). …

Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological
processes 1 , 2 and molecular mechanisms that are often specific to cell type 3 , 4 . …

Carvedilol is among the most effective β-blockers for improving survival after myocardial
infarction. Yet the mechanisms by which carvedilol achieves this superior clinical profile are still …

… Victor Jun-Yu Lim , Victor Jun-Yu Lim … Jin-Fang Chai, Shih-Ling Kao, Chaolong Wang,
Victor Jun-Yu Lim, Ing Wei Khor, Jinzhuang Dou, Anna I Podgornaia, Sonia Chothani, Ching-Yu …

Sepsis is characterized by a dysregulated inflammatory response to infection. Despite studies
in mice, the cellular and molecular basis of human sepsis remains unclear and effective …

G‐protein‐coupled receptor (GPCR) is an important target class of proteins for drug discovery,
with over 27% of FDA‐approved drugs targeting GPCRs. However, being a membrane …

Objective Hemoglobin A1c (HbA1c) accuracy is important for diabetes diagnosis and
estimation of overall glycemia. The G6PD-Asahi variant which causes glucose-6-phosphate …