User profiles for Vikram Saini

Vikram Saini

- Verified email at aiims.edu - Cited by 1670

Vikram Saini

- Verified email at upmc.edu - Cited by 397

[HTML][HTML] Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis

V Saini, KC Chinta, VP Reddy, JN Glasgow… - Nature …, 2020 - nature.com
Hydrogen sulfide (H 2 S) is involved in numerous pathophysiological processes and shares
overlapping functions with CO and •NO. However, the importance of host-derived H 2 S in …

[PDF][PDF] Ergothioneine maintains redox and bioenergetic homeostasis essential for drug susceptibility and virulence of Mycobacterium tuberculosis

V Saini, BM Cumming, L Guidry, DA Lamprecht… - Cell reports, 2016 - cell.com
The mechanisms by which Mycobacterium tuberculosis (Mtb) maintains metabolic equilibrium
to survive during infection and upon exposure to antimycobacterial drugs are poorly …

[HTML][HTML] Design, synthesis, DFT, docking studies and ADME prediction of some new coumarinyl linked pyrazolylthiazoles: Potential standalone or adjuvant …

S Kumar, V Saini, IK Maurya, J Sindhu, M Kumari… - PloS one, 2018 - journals.plos.org
The control of antimicrobial resistance (AMR) seems to have come to a dead end. The major
consequences of the use and abuse of antibacterial drugs are the development of resistant …

A systematic approach for developing bacteria-specific imaging tracers

…, EA Weinstein, LE Bambarger, V Saini… - Journal of Nuclear …, 2017 - Soc Nuclear Med
The modern patient is increasingly susceptible to bacterial infections including those due to
multidrug-resistant organisms (MDROs). Noninvasive whole-body analysis with pathogen-…

[HTML][HTML] Exploring salivary diagnostics in COVID-19: a scoping review and research suggestions

…, OP Kharbanda, D Bablani Popli, K Gautam, V Saini - BDJ open, 2021 - nature.com
Introduction Molecular diagnostics for SARS-CoV-2 infection characteristically involves the
sampling of the throat or nasopharyngeal swab (NPS). However, these procedures are …

Redox homeostasis in mycobacteria: the key to tuberculosis control?

A Kumar, A Farhana, L Guidry, V Saini… - Expert reviews in …, 2011 - cambridge.org
Mycobacterium tuberculosis (Mtb) is a metabolically flexible pathogen that has the extraordinary
ability to sense and adapt to the continuously changing host environment experienced …

[HTML][HTML] Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection

…, MA Rahman, DA Lamprecht, KH Rohde, V Saini… - PLoS …, 2017 - journals.plos.org
Signals modulating the production of Mycobacterium tuberculosis (Mtb) virulence factors
essential for establishing long-term persistent infection are unknown. The WhiB3 redox …

[HTML][HTML] Development of a highly effective low-cost vaporized hydrogen peroxide-based method for disinfection of personal protective equipment for their selective …

V Saini, K Sikri, SD Batra, P Kalra, K Gautam - Gut pathogens, 2020 - Springer
Background Personal Protective Equipment (PPE) is required to safely work with biological
agents of bacterial (ie Mycobacterium tuberculosis) or viral origin (Ebola and SARS). COVID-…

[HTML][HTML] Polyphasic Taxonomic Analysis Establishes Mycobacterium indicus pranii as a Distinct Species

V Saini, S Raghuvanshi, GP Talwar, N Ahmed… - PloS one, 2009 - journals.plos.org
Background Mycobacterium indicus pranii (MIP), popularly known as Mw, is a cultivable,
non-pathogenic organism, which, based on its growth and metabolic properties, is classified in …

Synthesis, characterization and utility of a series of novel copper (II) complexes as excellent surface disinfectants against nosocomial infections

…, A Kumar, E Zangrando, R Kataria, V Saini - Dalton …, 2021 - pubs.rsc.org
Nosocomial infections are among the major public health concerns, especially during the
ongoing Covid19 pandemic. There is a great demand for novel chemical agents that are …