User profiles for Vikram V. Kulkarni

Vikram Kulkarni

PhD, Rice University
Verified email at rice.edu
Cited by 1077

A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo

…, SM Chan, E Gitlin, VV Kulkarni… - Proceedings of the …, 2020 - National Acad Sciences
There is a strong need for a new broad-spectrum antiinfluenza therapeutic, as vaccination
and existing treatments are only moderately effective. We previously engineered a lectin, …

Postural analysis of building construction workers using ergonomics

VS Kulkarni, RV Devalkar - International Journal of Construction …, 2019 - Taylor & Francis
Ergonomics deals with the study of internal and external stresses acting on the human body.
Use of ergonomic principles reduces fatigue experienced by the human body in various …

Inducible lung epithelial resistance requires multisource reactive oxygen species generation to protect against viral infections

…, J Pantaleón García, AK Plumer, VV Kulkarni… - MBio, 2018 - Am Soc Microbiol
Viral pneumonias cause profound worldwide morbidity, necessitating novel strategies to
prevent and treat these potentially lethal infections. Stimulation of intrinsic lung defenses via …

Inducible epithelial resistance protects mice against leukemia-associated pneumonia

MM Leiva-Juárez, HH Ware, VV Kulkarni… - Blood, The Journal …, 2016 - ashpublications.org
Despite widespread infection prevention efforts, pneumonia remains the leading cause of
death among patients with acute leukemia, due to complex disease- and treatment-dependent …

[HTML][HTML] Inducible lung epithelial resistance requires multisource reactive oxygen species generation to protect against bacterial infections

HH Ware, VV Kulkarni, Y Wang, J Pantaleón García… - PLoS …, 2019 - journals.plos.org
Pneumonia remains a global health threat, in part due to expanding categories of susceptible
individuals and increasing prevalence of antibiotic resistant pathogens. However, …

[PDF][PDF] OBIF: an omics-based interaction framework to reveal molecular drivers of synergy

J Pantaleón García, VV Kulkarni… - NAR Genomics and …, 2022 - academic.oup.com
Bioactive molecule library screening may empirically identify effective combination therapies,
but molecular mechanisms underlying favorable drug–drug interactions often remain …

[HTML][HTML] Antimicrobial mitochondrial reactive oxygen species induction by lung epithelial immunometabolic modulation

Y Wang, VV Kulkarni, J Pantaleón García… - PLoS …, 2023 - journals.plos.org
Pneumonia is a worldwide threat, making discovery of novel means to combat lower
respiratory tract infection an urgent need. Manipulating the lungs’ intrinsic host defenses by …

Redox-Dependent Activation of Lung Epithelial STAT3 Is Required for Inducible Protection against Bacterial Pneumonia

VV Kulkarni, Y Wang, J Pantaleon Garcia… - American journal of …, 2023 - atsjournals.org
The lung epithelium is dynamic, capable of considerable structural and functional plasticity
in response to pathogen challenges. Our laboratory has demonstrated that an inhaled …

Plasmon-induced hot carriers in metallic nanoparticles

A Manjavacas, JG Liu, V Kulkarni, P Nordlander - ACS nano, 2014 - ACS Publications
Plasmon-induced hot carrier formation is attracting an increasing research interest due to its
potential for applications in photocatalysis, photodetection and solar energy harvesting. …

Development of a corticosteroid-immunosuppressed mouse model to study the pathogenesis and therapy of influenza-associated pulmonary aspergillosis

…, Y Jiang, K Bhoda, VV Kulkarni… - The Journal of …, 2023 - academic.oup.com
Influenza-associated pulmonary aspergillosis (IAPA) is a feared complication in patients
with influenza tracheobronchitis, especially those receiving corticosteroids. Herein, we …