Vaccines and therapies are urgently needed to address public health needs stemming from
emerging pathogens and biological threat agents such as the filoviruses Ebola virus (EBOV) …

In the present study, we have investigated processing and maturation of the envelope
glycoprotein (GP) of Ebola virus. When GP expressed from vaccinia virus vectors was analyzed by …

The taxonomy of the family Filoviridae (marburgviruses and ebolaviruses) has changed
several times since the discovery of its members, resulting in a plethora of species and virus …

The members of the family Filoviridae, Marburg virus (MBGV) and Ebola virus (EBOV), are
very similar in terms of morphology, genome organization, and protein composition. To …

Ebola virus (EBOV) infection blocks cellular production of alpha/beta interferon (IFN-α/β)
and the ability of cells to respond to IFN-α/β or IFN-γ. The EBOV VP35 protein has previously …

In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae
and Sunviridae), the elevation of the paramyxoviral subfamily …

The glycoprotein gene of Ebola virus contains a translational stop codon in the middle, thus
preventing synthesis of full-length glycoprotein. Twenty percent of the mRNA isolated from …

To study the mechanisms underlying the high pathogenicity of Ebola virus, we have established
a system that allows the recovery of infectious virus from cloned cDNA and thus permits …

Replication-competent recombinant vesicular stomatitis viruses (rVSVs) expressing the type
I transmembrane glycoproteins and selected soluble glycoproteins of several viral …

In 2017, the order Mononegavirales was expanded by the inclusion of a total of 69 novel
species. Five new rhabdovirus genera and one new nyamivirus genus were established to …