Background: The development of highly scalable single-cell transcriptome technology has
resulted in the creation of thousands of datasets, >30 in the retina alone. Analyzing the …

The advent of cell culture-based methods for the establishment and expansion of human
corneal endothelial cells (CEnC) has provided a source of transplantable corneal endothelium, …

The zinc finger e-box binding homeobox 1 (ZEB1) transcription factor is a master regulator
of the epithelial to mesenchymal transition (EMT), and of the reverse mesenchymal to …

Background In response to a wound, fibroblasts are activated to migrate toward the wound,
to proliferate and to contribute to the wound healing process. We hypothesize that changes …

Purpose This study reports the clinical features and genetic bases of 3 previously unreported
families with punctiform and polychromatic pre-Descemet corneal dystrophy (PPPCD). …

Purpose: To create a high-performance reactive web application to query single-cell gene
expression data across cell type, species, study, and other factors. Methods: We updated the …

De novo transcriptome construction from short-read RNA-seq is a common method for
reconstructing previously annotated and novel mRNA transcripts within a given sample. However, …

Methods: Primary CEnC were prepared from age-matched donor corneas using two
isolation/growth protocols, Tryp-LN-F99 or ColA-ColIV-M4M5. To measure cell adhesion we used …

Vitamin D has been found to be useful for a number of conditions. Various studies have
found it useful in different disorders to varying degree. It is being prescribed very frequently in …

Synthesis of three N-(aryl)-4-methoxybenzenesulfonamides of the general formula,(4-OCH3)
C6H4-SO2NH-C6H4 (iX)[where iX= H (1), 4-OCH3 (2) & 4-Cl (3)], by the reaction between …